THE NEW YORK JOURNAL OF PHARMACY 



as modified by himself. The method is 

 as follows: To the suspected oil is 

 added about one-fourth of its own vol- 

 ume of alcohol. The mixture is now 

 subjected to distillation, and 5 to 10 

 cubic centimeters of distillate collected. 

 The distillate is then mixed with an 

 equal volume of an acetylaceton-thal- 

 lium solution. This solution is pre- 

 pared by boiling for a protracted period 

 thallium carbonate with acetylaceton 

 dissolved in alcohol. In this manner 

 an alcoholic solution of acetyl-aceton 

 thallium is obtained. This reagent re- 

 acts with carbon disulphide with for- 

 mation of a voluminous precipitate 

 possessing an orange-yellow color. 

 Depending upon the quantity of carbon 

 disulphide present in the suspected oil 

 there will be noted at once or after 

 standing, a yellowish turbidity, and 

 sooner or later the characteristic yel- 

 low-orange precipitate will be noted. 

 The author states that the presence of 

 1% of carbon disulphide, or even lesser 

 quantities, can be shown with cer- 

 tainty. Oils containing sulphur com- 

 pounds among their components, do not 

 respond to the test. Another method 

 described by Utz, is that of E. Schmidt, 

 and is as follows: The suspected oil 

 is placed in a retort and connected with 

 a condenser and distilled on water- 

 bath. The distillate is received in a 

 small quantity of absolute alcohol. 

 After the distillation • is completed 

 the condenser tube is washed out 

 with absolute alcohol, and the wash- 

 ings mixed with the distillate. A 

 small quantity of alcoholic potash is 

 now added and the mixture heated 

 gently. xA.fter cooling the mixture is 

 acidified with acetic acid, and a solu- 

 tion f)f copper sulphate is added. In 



the presence of carbon disulphide a yel- 

 low precipitate of suboxide of copper 

 will form either at once or after stand- 

 ing for several hours. 



Treatment of Hay Fever. 



H. E. Goetz reports upon the results 

 of his investigations in the treatment 

 of hay fever or Coryza vasomotorica 

 periodica, describing a method which in 

 his hands produced much better results 

 than some of the older methods of 

 treatment. In persons subjected to 

 this very troublesome disorder Goetz 

 recommends, beginning several weeks 

 prior to the expected attack, or time 

 when the attack may be expected, 

 spraying of the mucous membrane of 

 the nose with Dobell's solution, night 

 and morning, followed by spraying 

 with a 10% solution of camphor-men- 

 thol in paraffin. 



The patient who has already been 

 subjected to an attack of hay fever, and 

 where the disease is well established, 

 is at once given the following: 



B Dionin 0.01500 



Atropin, sulf 0.00012 



Cafifein, citric 0.00750 



M. f. pulv. det. in caps amyl. 



This dose is repeated every two 

 hours until such time as the mouth and 

 nasal cavity becomes dry, and then is 

 repeated every four hours to prevent 

 a recurrence of symptoms. The author 

 states that after the ingestion of several 

 doses of the powder the patient feels 

 much relieved, and, except in very se- 

 vere cases, is abie to follow his usual 

 vocation. He ascribes this favorable 

 action to the combined efifect of all 

 three medicaments. He further states 

 that he has not noted any disagreeable 



