10 



THE NEW YORK JOURNAL OF PHARMACY 



Muenchcner Med. Wochensch. 1914- 

 report as follows : 



In their experiments they employed 

 T.ecutyl-Bayer, a solution of an organic 

 copper combination, each cubic centi- 

 meter of which equals, o.oi of copper, 

 the remedy was employed externally, 

 bv inunction, in form of an ointment, 

 also in the form of intravenous and in- 

 tramuscular injections. 



Treatment by inunction was soon 

 al)and.oned, because of severe skin ir- 

 ritation produced, as was medication 

 Jiv means of administration of capsules 

 containing the remedy. The gastric ir- 

 ritation in the latter case was very 

 severe and of long duration. 



Intramuscular injections were in all 

 cases painful, despite the use of novo- 

 caine. Intravenous injections, under 

 observance of proper care, were usual- 

 ly painless. The remedy is employed 

 in quantities of ^^ cubic centimeter, 

 gradually increased to 2.50 cubic centi- 

 meters, each dose being diluted with 

 from 5 to 10 cubic centimeters of 

 psysiological salt solution, and admin- 

 istered twice a week. In some cases 

 the injections were followed by an in- 

 crease of temperature, vomiting and 

 diarrhoea. In one case the catarrhal 

 condition of the lungs was much in- 

 creased. 



In only 18 of the cases was it possi- 

 ble to continue the treatment for the 

 prescribed length of time, in all others, 

 because of the side effects, the treat- 

 ment had to be discontinued. Improve- 

 ment was noted in the case of 8 pa- 

 tients, neither of whom however was 

 suffering from the disease in an ad- 

 vanced stage. All advance stage cases 

 resulted fatally. The observers came 

 to the conclusion that while the remedy 



did not produce harmful results, it 

 could not be claimed that its action 

 was jjeneficial. In such cases as were 

 seemingly benefited by this mode of 

 treatment, it was a question whether 

 the results^ obtained were not possibly 

 due to the general Ix'tter surroundings 

 in which the patients found themselves. 



ARTIFICIAL SPONGES. 



These may be made from Viskose, 

 a xanthogenic acid ester of cellulose. 

 This substance is treated with an aque- 

 ous solution of caustic soda, until the 

 mixture is of uniform consistence, and 

 is allowed to stand for a period of sev- 

 eral days. The dough like mass is then 

 kneaded with hemp fibres cut short, 

 and selected crystals of sodium sul- 

 phate. The size of the latter will de- 

 termine the pores (size of) in the arti- 

 ficial sponge. Pieces of convenient 

 size are cut out of the doughy mass, 

 and .'subjected to the action of diluted 

 sulphuric acid, which will cause the 

 viscose to coagulate, and become water 

 insoluble. The cyrstals of sodium sul- 

 phate are removed by dissolving in 

 water. 



MV5ICAL OMANIZATIOMS 



ORCHESTRA. 



Friday evening, November 20, the 

 Orchestra held its Annual Meeting 

 with Mr. Kinane in the chair. Mr. 

 Ambrose was re-elected Director, Miss 



