i68 THE JOURNAL OF PHARMACOLOGY. 



New Remedies. 



Eugallol, Pyrogallol mono-acetate. — This is a brown yellow syrupy 

 body, and is very soluble in water and acetone. It is found on the mar- 

 ket in form of a 33^ acetone solution, and in this form is employed as an 

 external application in cases of psoriasis, coating the parts to which it is 

 applied with a varnish-like film. 



Lenigallol, Pyrogallol tri-acetate. — This derivative of pyrogallol, un- 

 like its mother substance, does not exhibit any poisonous symptoms 

 when applied to the skin, even in very large doses (lenigallol, lanolin 

 aa 10.0 gm), It occurs as a white powder, insoluble in water, and is de- 

 composed hy alkalies. It can be employed in ointment form in cases of 

 acute and subacute eczema. Clothing is not stained by it. 



Saligallol, Pyrogallol di-salicylate. — Occurs in forms of a resin-like 

 body, very tough, and soluble in 2 parts of acetone and 15 parts of chloro- 

 form. It may be employed in place of lenigallol. " Solutio Saligolli " 

 is a 66 fo solution of the substance in acetone. 



Eunol a and ft . — Are combinations obtained by interaction between 

 maphtolen and eucalytolen. Both are very bitter, insoluble in water, but 

 very soluble in alcohol, ether, chloroform and olive oil. They find em- 

 ployment in surgical and dermatological practice. 



Galloformin — This compound is obtained by action of hexa-methylen- 

 tetramin on gallic acid. It forms very hard, highly refractive crystals, 

 which are employed in surgical and medical practice. 



Guacamphol (camphoric acid ester of guaiacol). — Is a valuable remedy 

 to combat night sweats of phthisis as well as the form of diarrhcea which 

 accompanies the disease. It crystallizes in shape of white needles, which 

 are devoid of odor and taste. 



A New Reaction to Distinguish Guaiacol from Creosote. — One 

 drop of a very dilute solution of formal (ifo formaldehyde) is added to 

 one drop of an aqueous solution of guaiacol, contained in a porcelain 

 capsule. To this mixture is added 1 cc. concentrated sulphuric acid, drop 

 by drop, by means of a pipette. As soon as the liquids come in contact, 

 the lower portion assumes a bright violet color, which gradual^ imparts 

 itself to the entire body of liquid. A solution of guaiacol alone with 

 sulphuric acid turns green. Creosote, when treated with solution of 

 formal and sulphuric acid, also yields a violet color, with a decided crimson 

 tint, however. Upon adding the acid a flocculent precipitate also separ- 

 ates, the flocculi having a carmine color. In the case of guaiacol no such 

 flocculi are seen, the mixture remaining perfectly clear. If acetaldehyde 

 is employed the color produced in case of creosote is decidedly carmine 

 without a trace of violet. G. C. D. 



