24 



The later development given in part IV. "Histogenesis and Morphogenesis 

 of the Organ Systems", is discussed according to organ systems and forms the 

 part in which comparative embryological and comparative anatomical aspects 

 have been combined. The diversity is. however, so enormous in the development 

 and adaptations of each organ system among the various classes, orders 

 and families of the Vertebrates that a survey can only be an outline of the 

 more principal aspects. This part of the book therefore unavoidably gets a 

 somewhat superficial character since the general comprehensive scope of the 

 book has also been maintained here. The same holds for the last part, "Care 

 and Nourishment of the Developing Young". We therefore feel that the 

 second half of this handbook will he more used for teaching purposes, whereas 

 the first half will also be highly appreciated by scientists as one of the more 

 comprehensive and excellent reviews of our knowledge of the various processes 

 and events in development. 



The references at the end of each chapter form an excellent key to the older 

 and recent original literature. The entire book has been very well organized 

 and has been written in an easy style. The numerous illustrations have partially 

 been chosen with much care from other handbooks and publications and have 

 partially been newly made. Particularly the last category is very outstanding 

 and might serve as an example for many textbooks. The only suggestion we 

 should like to make concerns the use of different characters in the text and 

 particularly in the headings. A better choice can markedly increase the survey- 

 ability of the text, now e.g. the italics used for heading of the larger units 

 do not strike the eye sufficiently, whereas the text in bold type gets too 

 much emphasis. 



All in all it has been a great pleasure to reviev/ this handbook which we not 

 only highly recommend to all embryologists. but of which we Hke to say that 

 it should be within direct reach of all embryologists, teachers and students 

 directing respectively attending courses in embryology. 



P. D. NIEUWKOOP 



"TISSUE CULTURE" 

 Second Edition, 1954 

 by E. N. Willmer Methuen & Co. Ltd., London 



with 175 pp.. 2 plates John Wiley & Sons. Inc.. New York 



and 8 text diagrams Price: 9 s. 6 d. 



As the author states in the preface this book will merely give a fair account 

 of the part played by the method of tissue culture in the elucidation of the 

 problems of normal growth and differentiation and in the study of the normal 

 development of the animal. He has very successfully tried to give a survey of 

 the main advances made in our knowledge of growth and differentiation as far 

 as the technique of tissue culture has been employed. Since the first edition in 

 1935 very great advances have been made by the development of the phase- 

 contrast, the electron and the reflecting microscopes as well as by the use of 

 tracer elements and by the developments in bio- and histochemistry, so that 

 a second edition was highly desirable. This book actually gives a very clear 

 and comprehensive survey on the many aspects of unorganized cell growth and 

 differentiation as well as on those of organized growth of tissues and organ 

 systems. It contains a glossary, a list of reference books on tissue culture 



