﻿500 
  Sevextji 
  Anmal 
  Report 
  of 
  the 
  

  

  Experimental 
  Tuberculosis. 
  

   Bollinger 
  made 
  intraperitoneal 
  inoculation 
  of 
  a 
  three-monthsr 
  

   old 
  calf 
  with 
  liquid 
  from 
  a 
  tuberculous 
  human 
  lung, 
  and 
  killed 
  

   the 
  subject 
  seven 
  months 
  later. 
  Fibroid 
  pedieulated 
  tumors^ 
  

   ranging 
  in 
  size 
  from 
  a 
  pea 
  to 
  a 
  walnut, 
  hung 
  from 
  the 
  mesentery 
  

   and 
  spleen, 
  and 
  the 
  mesenteric 
  and 
  retroperitoneal 
  glands 
  Avere 
  

   tuberculous. 
  (Munch 
  med. 
  Wochenschr., 
  1894.) 
  

  

  Sidney 
  Martin 
  fed 
  four 
  calves 
  seventy 
  c. 
  c. 
  sputum, 
  containing 
  a 
  

   large 
  number 
  of 
  bacilli. 
  Three 
  killed, 
  after 
  four, 
  eight 
  and 
  twelve 
  

   weeks, 
  respectively, 
  had 
  fifty-three, 
  sixty-three 
  and 
  thirteen, 
  nodulea 
  

   respectively 
  in 
  the 
  small 
  intestines, 
  mostly 
  in 
  Peyers' 
  patches. 
  The 
  

   fourth, 
  killed 
  after 
  thirty-three 
  weeks, 
  showed 
  no 
  lesion. 
  

  

  Two 
  calves 
  receiving 
  at 
  one 
  dose 
  440 
  c. 
  c. 
  sputum, 
  containing 
  

   a 
  large 
  number 
  of 
  bacilli, 
  were 
  killed 
  after 
  eight 
  and 
  nineteen 
  

   weeks. 
  The 
  first 
  had 
  tuberculous 
  nodules 
  in 
  the 
  intestine 
  and 
  mes- 
  

   enteric 
  glands; 
  the 
  second 
  show^ed 
  no 
  lesion. 
  (Eepoi-t 
  of 
  Hoyal 
  

   Commission 
  on 
  Tuberculosis.) 
  

  

  Frothingham 
  injected 
  into 
  the 
  peritoneum 
  of 
  two 
  calves, 
  three 
  

   and 
  thirteen 
  weeks 
  old, 
  a 
  culture 
  of 
  bacilli, 
  isolated 
  one 
  vear 
  before 
  

   from 
  the 
  liver 
  of 
  a 
  child. 
  Slight 
  local 
  nodules 
  only 
  were 
  pro- 
  

   duced, 
  some 
  like 
  spontaneous 
  tubercle, 
  others 
  granulation 
  tissue. 
  

   Two 
  other 
  calves, 
  three 
  weeks 
  and 
  two 
  months 
  old, 
  were 
  injected 
  

   in 
  the 
  trachea. 
  One 
  had 
  a 
  large 
  local 
  abcees 
  in 
  the 
  neck, 
  with 
  a 
  

   small 
  number 
  of 
  tubercles 
  (without 
  bacilli) 
  in 
  the 
  lungs 
  and 
  liver. 
  

   The 
  other 
  showed 
  no 
  lesion. 
  AVith 
  the 
  advance 
  of 
  the 
  disease 
  

   along 
  the 
  lymph 
  channels 
  to 
  the 
  glands, 
  lungs 
  and 
  liver, 
  there 
  was 
  

   a 
  promise 
  of 
  further 
  dcA'elopment 
  under 
  more 
  favorable 
  condi- 
  

   tions 
  of 
  life. 
  

  

  The 
  sanitary 
  significance 
  of 
  the 
  intercommunication 
  of 
  tubercu- 
  

   losis 
  between 
  man 
  and 
  animals, 
  and 
  the 
  importance 
  of 
  methods 
  of 
  

   diagnosing 
  the 
  disease 
  in 
  its 
  early 
  stage 
  in 
  cattle, 
  rendered 
  it 
  desir- 
  

   able 
  to 
  obtain 
  the 
  opinion 
  of 
  those 
  thoroughly 
  versed 
  in 
  the 
  matter. 
  

   Dr. 
  James 
  Law, 
  director 
  of 
  the 
  jSTew 
  York 
  State 
  Veterinary 
  Col- 
  

   lege, 
  was 
  requested, 
  therefore, 
  to 
  prepare 
  a 
  statement 
  concerning 
  

  

  