﻿Commissioner 
  of 
  Ageicultuee. 
  547 
  

  

  " 
  III. 
  Results 
  of 
  last 
  experiment 
  hi 
  inoculating 
  cattle 
  ivith 
  

   hovine 
  and 
  human 
  (sputum) 
  tubercle 
  hacilli. 
  The 
  points 
  of 
  

   difference 
  between 
  the 
  inoculated 
  disease 
  produced 
  by 
  these 
  bacilli 
  

   are 
  several. 
  1. 
  The 
  bo^dne 
  cases 
  either 
  remained 
  stationary 
  in 
  

   weight 
  or 
  lost 
  slightly, 
  while 
  the 
  sputum 
  cases 
  gained 
  75 
  to 
  85 
  

   pounds. 
  Still, 
  the 
  age 
  of 
  one 
  of 
  the 
  bovine 
  cases 
  may 
  be 
  partly 
  

   responsible 
  for 
  stationary 
  weight. 
  2. 
  There 
  was 
  marked 
  fever 
  

   in 
  the 
  bovine 
  cases 
  for 
  three 
  weeks 
  after 
  the 
  inoculation; 
  prac- 
  

   tically 
  none 
  in 
  the 
  sputum 
  cases. 
  3. 
  There 
  were 
  well-marked 
  

   differences 
  in 
  the 
  lesions 
  produced. 
  In 
  the 
  sputum 
  cases 
  the 
  

   lesions 
  are 
  nearly 
  the 
  same, 
  and 
  consist 
  in: 
  (a) 
  A 
  tumor 
  in 
  the 
  

   right 
  caudal 
  lobe 
  of 
  the 
  lung, 
  about 
  one 
  inch 
  in 
  diameter, 
  project- 
  

   ing 
  somewhat 
  above 
  the 
  surface 
  of 
  the 
  lung. 
  This 
  represents 
  the 
  

   place 
  where 
  the 
  needle 
  penetrated 
  into 
  the 
  lung 
  tissue 
  and 
  depos- 
  

   ited 
  the 
  tubercle 
  bacilli. 
  In 
  each 
  case 
  the 
  contents 
  of 
  this 
  tumor 
  

   were 
  softened 
  and 
  converted 
  into 
  a 
  curdy 
  mass, 
  enclosed 
  in 
  a 
  thin- 
  

   walled 
  capsule, 
  smooth 
  internally. 
  The 
  disease 
  was 
  not 
  spreading 
  

   from 
  this 
  point, 
  nor 
  were 
  tubercles 
  visible 
  in 
  the 
  lymph-glands 
  of 
  

   the 
  lungs 
  and 
  tlmrax, 
  excepting 
  in 
  one 
  gland 
  of 
  No. 
  39 
  (Sputum 
  

   v.). 
  (h) 
  The 
  free 
  margin 
  of 
  the 
  right 
  lung 
  and 
  the 
  pleural 
  cover- 
  

   ing 
  of 
  the 
  ribs 
  on 
  the 
  right 
  side 
  w^ere 
  beset 
  with 
  a 
  new 
  formation 
  

   of 
  loose 
  vascular 
  fringes 
  or 
  shreds, 
  in 
  which 
  in 
  only 
  one 
  case 
  some 
  

   minute 
  nodules 
  could 
  be 
  felt, 
  and 
  some 
  flattish, 
  pediculated 
  masses, 
  

   which 
  did 
  not 
  resemble 
  tubercles 
  at 
  all 
  histologically, 
  or 
  which 
  

   were 
  only 
  abortive 
  forais 
  of 
  the 
  same. 
  

  

  "Among 
  the 
  bovine 
  cases 
  we 
  have 
  the 
  follomng 
  characteristic 
  

   points 
  to 
  note 
  : 
  (a) 
  Disseminated 
  tuberculosis 
  of 
  the 
  lungs, 
  severest 
  

   and 
  fatal 
  in 
  oSTo. 
  71, 
  the 
  youngest; 
  least 
  pronounced 
  in 
  the 
  oldest, 
  

   !N^o. 
  88. 
  Associated 
  with 
  this 
  a 
  local, 
  disintegrated 
  focus 
  in 
  the 
  

   lungs 
  of 
  'No. 
  88. 
  (h) 
  Tuberculous 
  deposits 
  on 
  th-e 
  lungs, 
  perioar- 
  

   dium, 
  diaphragm, 
  and 
  the 
  ribs, 
  resembling 
  closely 
  the 
  products 
  of 
  

   the 
  natural 
  disease 
  in 
  cattle. 
  Extension 
  of 
  the 
  eruption 
  to 
  the 
  

   costal 
  pleura 
  of 
  the 
  left 
  side, 
  (c) 
  Extensive 
  tuberculosis 
  of 
  all 
  or 
  

   nearly 
  all 
  th-e 
  lymph-glands 
  of 
  the 
  thorax, 
  including 
  both 
  medi- 
  

  

  