﻿548 
  Sevkmii 
  A.NMAi. 
  Kkpokt 
  of 
  the 
  

  

  astiii:;! 
  ( 
  liaiiis. 
  (d) 
  Sliulit 
  tiil:oivr,h»?i- 
  of 
  other 
  organs 
  — 
  spleen, 
  

   ]ivei'. 
  ami 
  kidney 
  — 
  in 
  two 
  cnit 
  of 
  tliiee 
  cases. 
  

  

  " 
  A 
  summary 
  of 
  the 
  three 
  separate 
  tests 
  on 
  cattle 
  (including 
  the 
  

   I)ul>li>lied 
  experiment), 
  in 
  ^vllich 
  twelve 
  animals 
  were 
  used, 
  shows 
  

   tli'at 
  six 
  animals 
  w'ere 
  inoculated 
  with 
  human 
  bacilli, 
  ilvc 
  with 
  

   bovine 
  bacilli; 
  one 
  animal 
  was 
  inoculated 
  Avith 
  swine 
  bacilli. 
  

   Of 
  the 
  sputum 
  cases, 
  one 
  showed 
  no 
  disease; 
  two 
  showed 
  very 
  

   sliaht 
  lesions, 
  three 
  showed 
  onlv 
  hu-al 
  Ic-iuns 
  without 
  dissemi- 
  

   nation. 
  Of 
  th'e 
  bovine 
  cases, 
  two 
  died 
  of 
  generalized 
  disease; 
  tw'o 
  

   showed 
  extensive 
  lesions; 
  one 
  showed 
  less 
  exi:ensive 
  lesions. 
  In 
  

   the 
  swine 
  case 
  the 
  lesions 
  were 
  less 
  extensive 
  than 
  in 
  the 
  bovine 
  

   cases. 
  In 
  the 
  guinea-pig 
  few 
  well-defined 
  differences 
  were 
  found, 
  

   owing 
  to 
  the 
  great 
  susceptibility 
  of 
  this 
  species."' 
  

  

  The 
  most 
  conspicuous 
  differences 
  between 
  the 
  human 
  and 
  bovine 
  

   I)aciili 
  brought 
  out 
  by 
  these 
  experiments 
  is 
  the 
  marked 
  increase 
  in 
  

   virulence 
  of 
  tlve 
  bovine 
  over 
  the 
  sputum 
  bacillus, 
  especially 
  for 
  

   rabbits 
  aiid 
  cattle. 
  This 
  result 
  has 
  already 
  been 
  confirmed 
  by 
  

   Adami^- 
  and 
  Pearson.^^ 
  

  

  In 
  the 
  light 
  of 
  these 
  carefully 
  determined 
  differences 
  the 
  con- 
  

   clusions 
  that 
  there 
  are 
  varieties 
  or 
  races 
  of 
  tubercle 
  bacilli 
  cannot 
  

   be 
  gainsaid. 
  In 
  this 
  respect, 
  however, 
  they 
  do 
  not 
  differ 
  from 
  

   many 
  other 
  pathogenic 
  bacteria. 
  

  

  Concerning 
  the 
  differences 
  in 
  morphology 
  Pearson^'* 
  writes: 
  " 
  As 
  

   to 
  the 
  mori^hology, 
  I 
  would 
  say 
  that 
  this 
  can 
  be 
  changed 
  mate- 
  

   rially 
  by 
  passing 
  through 
  a 
  single 
  animal. 
  Tor 
  example, 
  if 
  a 
  cul- 
  

   tm-e 
  of 
  short, 
  thick 
  bacilli 
  from 
  the 
  cow 
  is 
  used 
  for 
  inoculating 
  

   the 
  i)ig 
  or 
  the 
  goat, 
  the 
  bacilli 
  recovered 
  after 
  the 
  death 
  of 
  the 
  

   inoculated 
  animal 
  are, 
  in 
  some 
  instances, 
  longer, 
  more 
  slender, 
  and 
  

   frequently 
  beaded." 
  

  

  Smith' 
  has 
  made 
  it 
  clear 
  that 
  for 
  certain 
  animals 
  the 
  bovine 
  

   variety 
  of 
  tubercle 
  bacillus 
  is 
  more 
  virulent 
  than 
  tlie 
  human 
  variety. 
  

   If 
  this 
  is 
  unifoi-mly 
  the 
  case, 
  as 
  it 
  seems 
  to 
  be, 
  for 
  nearly 
  all 
  ani- 
  

  

  22 
  Canadian 
  Journal 
  of 
  iledieine 
  and 
  Surgery, 
  December, 
  1899. 
  

   23Loc. 
  cit. 
  

   24Loc. 
  cit. 
  

  

  