﻿' 
  Commissioner 
  of 
  A(;r>TcrLTrRE. 
  r)49 
  

  

  mals, 
  Pearson 
  findiiio- 
  it 
  so 
  for 
  the 
  horse, 
  goat, 
  sheep, 
  pig, 
  dog, 
  cat, 
  

   guinea-pig, 
  and 
  rabbit, 
  is 
  it 
  not 
  possible 
  that 
  it 
  is 
  likewise 
  mere 
  

   vinilent 
  for 
  the 
  human 
  species? 
  In 
  a 
  report 
  on 
  tuberculosis 
  issiicd 
  

   by 
  tlve 
  Council 
  of 
  the 
  British 
  Medical 
  Association, 
  January 
  IS, 
  

   1890, 
  the 
  following 
  statement 
  is 
  made: 
  " 
  The 
  mortality 
  from 
  tu- 
  

   berculosis 
  in 
  early 
  childhood 
  is 
  not 
  decreasing 
  as 
  it 
  is 
  at 
  other 
  ages 
  

   in 
  the 
  United 
  Kingdom, 
  and 
  the 
  opinion 
  that 
  this 
  great 
  prevalence 
  

   of 
  the 
  disease 
  in 
  infancy 
  and 
  childh'ood 
  is 
  due 
  to 
  infection 
  throuch 
  

   the 
  alimentary 
  canal 
  by 
  milk 
  from 
  tuberculous 
  cows 
  appears 
  to 
  

   l)e 
  well 
  founded." 
  

  

  It 
  is 
  unwise 
  to 
  speculate 
  upon 
  the 
  possibilities 
  so 
  long 
  as 
  there 
  

   is 
  hope 
  that 
  in 
  the 
  near 
  future 
  conclusive 
  evidence 
  may 
  be 
  recorded. 
  

   We 
  are 
  growing 
  in 
  the 
  knowledge 
  of 
  this 
  important 
  subject, 
  and 
  

   when 
  the 
  time 
  comes 
  we 
  will 
  know 
  the 
  truth. 
  At 
  present 
  we 
  have 
  

   convincing 
  proof 
  of 
  varieties 
  among 
  tubercle 
  bacilli, 
  but 
  it 
  never 
  

   has 
  been 
  stated, 
  so 
  far 
  as 
  I 
  can 
  learn, 
  by 
  those 
  competent 
  to 
  give 
  

   an 
  opinion, 
  that 
  human 
  and 
  bovine 
  tubercle 
  bacilli 
  are 
  specifically 
  

   different. 
  

  

  Appendix. 
  

  

  /. 
  Koch's 
  NciD 
  Tuhcrcidin. 
  

  

  After 
  the 
  discovery 
  of 
  tuberculin 
  Koch 
  again 
  turned 
  his 
  atten- 
  

   tinn 
  toward 
  the 
  discovery 
  of 
  a 
  substance 
  that 
  should 
  render 
  the 
  

   system 
  immune 
  to 
  the 
  bacilli 
  themselves. 
  He 
  experimented 
  for 
  

   over 
  a 
  year 
  with 
  a 
  normal 
  natron 
  lye 
  extract 
  of 
  tubercle 
  bacilli, 
  

   which 
  is 
  designated 
  as 
  tuhercle 
  antitoxin. 
  It 
  was 
  found 
  that 
  small 
  

   inje<3tions 
  of 
  this 
  substance 
  produced 
  results 
  analogous 
  to 
  those 
  of 
  

   tuberculin, 
  but 
  that 
  the 
  effects 
  lasted 
  somewhat 
  longer 
  and 
  were 
  

   more 
  certain. 
  Larger 
  doses 
  produced 
  abscesses 
  at 
  the 
  place 
  where 
  

   tlve 
  injections 
  were 
  made 
  that 
  could 
  only 
  be 
  explained 
  as 
  being 
  

   the 
  effect 
  of 
  the 
  dead 
  bacilli 
  contained 
  in 
  the 
  preparation. 
  The 
  

   bacteria 
  were 
  completely 
  removed 
  by 
  filtration, 
  and 
  it 
  was 
  found 
  

   that 
  no 
  more 
  abscesses 
  were 
  produced, 
  but 
  that 
  the 
  effects 
  of 
  th-e 
  

   injections 
  were 
  in 
  nowise 
  superior 
  to 
  those 
  of 
  tuberculin. 
  Tliis 
  

   discovery 
  led 
  Koch 
  to 
  the 
  conclusion 
  that 
  as 
  an 
  abscess 
  is 
  invari- 
  

  

  