﻿552 
  Seventh 
  Annual 
  liKroKT 
  or 
  the 
  

  

  lings 
  and 
  two-year-olds 
  should 
  receive 
  1 
  to 
  1.5 
  c.c, 
  according 
  to 
  

   size. 
  Uulls 
  and 
  very 
  large 
  animals 
  may 
  receive 
  3 
  c.c. 
  The 
  in- 
  

   jection 
  is 
  made 
  beneath 
  the 
  skin 
  of 
  the 
  neck 
  or 
  shoulders. 
  

  

  There 
  is 
  usually 
  no 
  marked 
  local 
  swelling 
  at 
  the 
  seat 
  of 
  the 
  

   injection. 
  There 
  is, 
  now 
  and 
  then, 
  uneasiness, 
  trembling, 
  and 
  

   more 
  frequent 
  passages 
  of 
  softened 
  dung. 
  There 
  may 
  also 
  be 
  

   slight 
  acceleration 
  of 
  the 
  pulse 
  and 
  of 
  the 
  breathing. 
  A 
  rise 
  in 
  

   temperature 
  on 
  the 
  day 
  following 
  the 
  injection 
  of 
  2° 
  F. 
  or 
  more 
  

   above 
  the 
  maximum 
  observed 
  on 
  the 
  previous 
  day 
  should 
  be 
  re- 
  

   garded 
  as 
  an 
  indication 
  of 
  tuberculosis. 
  For 
  any 
  rise 
  less 
  than 
  

   this 
  a 
  repetition 
  of 
  the 
  injection 
  after 
  three 
  to 
  six 
  weeks 
  is 
  highly 
  

   desirable. 
  In 
  rare 
  cases 
  the 
  temperature 
  may 
  rise 
  in 
  the 
  absence 
  

   of 
  any 
  disease; 
  it 
  may 
  fail 
  to 
  rise 
  when 
  tuberculosis 
  is 
  present. 
  

  

  It 
  is 
  hardlv 
  necessarv 
  to 
  suggest 
  that 
  for 
  the 
  convenience 
  of 
  

   the 
  one 
  taking 
  the 
  test 
  the 
  animals 
  should 
  not 
  be 
  turned 
  out, 
  but 
  

   fed 
  and 
  watered 
  in 
  the 
  stable. 
  It 
  is 
  desirable 
  to 
  make 
  note 
  of 
  

   the 
  time 
  of 
  feeding 
  and 
  watering. 
  

  

  II. 
  The 
  directions 
  for 
  using 
  tuberculin 
  issued 
  by 
  Prof. 
  Mc- 
  

   Fadyean,^^ 
  from 
  the 
  Eoyal 
  Veterinary 
  College, 
  London: 
  

  

  1. 
  While 
  under 
  the 
  tuberculin 
  test 
  cattle 
  ought 
  to 
  be 
  kept 
  in 
  

   the 
  house, 
  fed 
  on 
  their 
  usual 
  food, 
  and 
  protected 
  from 
  draughts. 
  

   2. 
  The 
  dose 
  of 
  tuberculin 
  for 
  a 
  medium-sized 
  cow 
  is 
  3 
  c.c. 
  or 
  50 
  

   minims, 
  and 
  it 
  may 
  be 
  varied 
  a 
  little 
  above 
  or 
  below 
  that, 
  accord- 
  

   ing 
  to 
  the 
  size 
  of 
  the 
  animal. 
  3. 
  It 
  ought 
  to 
  be 
  injected 
  under 
  

   the 
  skin 
  with 
  a 
  clean 
  hypodermatic 
  syringe. 
  The 
  most 
  convenient 
  

   points 
  are 
  in 
  front 
  of 
  the 
  shoulder 
  or 
  on 
  the 
  chest-wall 
  beneath 
  

   the 
  point 
  of 
  the 
  elbow. 
  The 
  best 
  form 
  of 
  syringe 
  is 
  one 
  with 
  an 
  

   asbestos 
  piston, 
  as 
  the 
  whole 
  instrument 
  may 
  be 
  sterilized 
  by 
  

   boiling 
  it 
  in 
  water 
  for 
  five 
  minutes 
  before 
  using. 
  4. 
  Th'e 
  tuber- 
  

   culin 
  must 
  be 
  injected 
  into 
  the 
  subcutaneous 
  connective 
  tissue, 
  

   and 
  care 
  must 
  be 
  taken 
  that 
  the 
  whole 
  dose 
  is 
  introduced. 
  5. 
  

   The 
  temperature 
  must 
  be 
  taken 
  at 
  the 
  time 
  of 
  the 
  injection, 
  and 
  

   at 
  the 
  sixth, 
  ninth, 
  tw^elfth, 
  and 
  fifteenth 
  hours 
  afterward. 
  6. 
  

  

  26 
  Legge. 
  Cattle 
  Tuberculosis, 
  1899. 
  

  

  