﻿CoMMissioxEK 
  OF 
  Agkicultuke. 
  , 
  553 
  

  

  Animals 
  in 
  -svliicli 
  the 
  temperature 
  during 
  the 
  fifteen 
  hours 
  fol- 
  

   lowing 
  the 
  injection 
  rises 
  gradually 
  to 
  104° 
  F. 
  or 
  more 
  may 
  be 
  

   classed 
  as 
  tuberculous, 
  and 
  those 
  in 
  which 
  it 
  remains 
  under 
  103° 
  

   F. 
  as 
  not 
  tuberculous. 
  When 
  the 
  maximum 
  temperature 
  attained 
  

   is 
  under 
  104° 
  F., 
  but 
  over 
  103° 
  F., 
  the 
  case 
  must 
  be 
  considered 
  

   doubtful, 
  and 
  the 
  animal 
  may 
  be 
  retested 
  after 
  a 
  month. 
  7. 
  The 
  

   test 
  is 
  not 
  reliable 
  in 
  the 
  case 
  of 
  animals 
  in 
  the 
  last 
  stages 
  of 
  the 
  

   disease 
  or 
  in 
  those 
  in 
  which 
  the 
  temperature 
  is 
  over 
  103° 
  F. 
  be- 
  

   fore 
  injection. 
  8. 
  The 
  tuberculin 
  should 
  be 
  kept 
  in 
  a 
  cool 
  place 
  

   and 
  protected 
  from 
  the 
  light. 
  Should 
  it 
  become 
  turbid 
  or 
  cloudy 
  

   it 
  must 
  not 
  be 
  used. 
  9. 
  The 
  tuberculin 
  test 
  does 
  not 
  render 
  the 
  

   milk 
  in 
  any 
  way 
  injurious. 
  

  

  III. 
  Recommendations 
  for 
  the 
  use 
  of 
  tuberculin 
  by 
  Prof. 
  Ed. 
  

   ISTocard, 
  Alfort 
  Veterinary 
  College, 
  France.^^ 
  

  

  1. 
  Tuberculin 
  possesses 
  an 
  indisputable 
  specific 
  action 
  on 
  tuber- 
  

   culous 
  cattle, 
  which 
  betrays 
  itself 
  especially 
  by 
  noteworthy 
  eleva- 
  

   tions 
  of 
  the 
  temperature, 
  2. 
  The 
  injection 
  of 
  a 
  strong 
  dose, 
  say 
  

   30 
  to 
  40 
  centigrammes, 
  according 
  to 
  the 
  size 
  of 
  the 
  subject, 
  gen- 
  

   erally 
  causes 
  in 
  tuberculous 
  animals 
  a 
  rise 
  of 
  temperature 
  be- 
  

   tw^een 
  1.5° 
  and 
  3°, 
  3. 
  The 
  same 
  dose 
  injected 
  into 
  healthy 
  cattle 
  

   causes 
  appreciable 
  febrile 
  action. 
  4. 
  The 
  febrile 
  reaction 
  appears 
  

   most 
  frequently 
  between 
  the 
  twelfth 
  and 
  fifteenth 
  hour 
  after 
  in- 
  

   jection, 
  sometimes 
  after 
  the 
  ninth 
  hour, 
  very 
  rarely 
  after 
  the 
  

   eighteenth, 
  and 
  always 
  lasts 
  several 
  hours. 
  5. 
  The 
  duration 
  and 
  

   intensity 
  of 
  the 
  reaction 
  have 
  no 
  relation 
  to 
  the 
  number 
  and 
  

   gravity 
  of 
  the 
  lesions; 
  it 
  seems, 
  even, 
  that 
  the 
  reaction 
  may 
  be 
  

   most 
  distinct 
  in 
  cases 
  where, 
  the 
  lesion 
  being 
  very 
  limited, 
  the 
  

   animal 
  has 
  retained 
  the 
  appearances 
  of 
  health. 
  6. 
  In 
  very 
  tuber- 
  

   culous 
  subjects 
  — 
  consumptives 
  in 
  the 
  true 
  sense 
  of 
  .the 
  word 
  — 
  

   especially 
  in 
  those 
  which 
  are 
  feverish, 
  the 
  reaction 
  may 
  be 
  little 
  

   marked 
  or 
  even 
  absolutely 
  nil. 
  7. 
  It 
  is 
  wise 
  to 
  take 
  the 
  tem- 
  

   perature 
  of 
  the 
  animals 
  morning 
  and 
  night 
  for 
  several 
  days 
  be- 
  

  

  27Xocard. 
  Animal 
  Tuberculosis, 
  1897. 
  

  

  