﻿Commissioner 
  of 
  Agricultuke. 
  53T 
  

  

  on 
  the 
  preceding 
  day. 
  The 
  elevation 
  should 
  come 
  on 
  gradually, 
  

   remaining 
  practically 
  at 
  its 
  f 
  astigium 
  for 
  a 
  few 
  hours, 
  and 
  gradu- 
  

   ally 
  subside. 
  Erratic 
  elevations 
  of 
  short 
  duration 
  are 
  to 
  be 
  ex- 
  

   cluded. 
  In 
  cases 
  of 
  doubt 
  the 
  animals 
  should 
  be 
  retested. 
  

  

  6. 
  Animals 
  advanced 
  in 
  pregnancy 
  and 
  those 
  known 
  to 
  be 
  suf- 
  

   fering 
  from 
  any 
  disease 
  or 
  in 
  oestrum 
  should 
  be 
  excluded. 
  All 
  

   methods 
  of 
  treatment, 
  including 
  exposure 
  to 
  cold, 
  kind 
  of 
  food 
  

   and 
  drink, 
  which 
  would 
  tend 
  to 
  modify 
  the 
  temperature 
  should 
  

   be 
  avoided. 
  Animals 
  in 
  which 
  the 
  disease 
  is 
  well 
  advanced 
  some- 
  

   times 
  fail 
  to 
  react. 
  

  

  1. 
  The 
  dose 
  should 
  vary 
  to 
  correspond 
  with 
  the 
  weight 
  of 
  the- 
  

   animal. 
  In 
  cases 
  of 
  a 
  second 
  test 
  within 
  a 
  few 
  days 
  the 
  quan- 
  

   tity 
  of 
  tuberculin 
  injected 
  should 
  be 
  larger 
  than 
  for 
  the 
  first 
  test. 
  

  

  As 
  the 
  tuberculin 
  reaction 
  consists 
  simply 
  in 
  a 
  temporary 
  hyper- 
  

   thermia, 
  which 
  is 
  ordinarily 
  thought 
  to 
  be 
  easily 
  determined, 
  it 
  is 
  

   not 
  infrequently 
  stated 
  that 
  the 
  precautions 
  imposed 
  in 
  its 
  appli- 
  

   cation 
  are 
  too 
  stringent. 
  In 
  the 
  bovine 
  species 
  the 
  normal 
  tem- 
  

   perature 
  varies, 
  in 
  comparison 
  with 
  man, 
  to 
  a 
  marked 
  degree. 
  In 
  

   189Y 
  a 
  series 
  of 
  temperature 
  determinations 
  on 
  healthy 
  animals- 
  

   were 
  made 
  under 
  my 
  directions 
  by 
  Drs. 
  Howe 
  and 
  Kyder.^^ 
  In 
  

   cattle 
  they 
  not 
  infrequently 
  found 
  a 
  variation 
  of 
  2°, 
  and 
  even 
  of 
  

   3°, 
  within 
  twenty-four 
  hours. 
  Cold 
  water, 
  when 
  drunk 
  in 
  con- 
  

   siderable 
  quantities, 
  lowered 
  the 
  temperature 
  from 
  2° 
  to 
  4° 
  (see- 
  

   chart). 
  A 
  temporary 
  excitement 
  usually 
  caused 
  an 
  elevation 
  of 
  

   from 
  1° 
  to 
  1.5° 
  F. 
  They 
  found 
  marked 
  variations 
  in 
  the 
  tem- 
  

   perature 
  of 
  the 
  same 
  animal 
  on 
  consecutive 
  days. 
  The 
  tempera- 
  

   ture 
  (taken 
  hourly 
  for 
  two 
  weeks) 
  at 
  12 
  noon 
  and 
  12 
  midnight 
  

   was 
  often 
  the 
  same. 
  In 
  some 
  cases 
  the 
  maximum 
  elevation 
  oc- 
  

   curred 
  near 
  midnight, 
  and 
  on 
  the 
  f 
  ollo^ving 
  day 
  the 
  minimum 
  tem- 
  

   perature 
  would 
  appear 
  at 
  that 
  time. 
  It 
  was 
  not 
  uncommon 
  for 
  

   the 
  maximum 
  temperature 
  to 
  occur 
  twice 
  a 
  day 
  and 
  occasionally 
  

   several 
  times 
  within 
  the 
  twenty-four 
  hours. 
  There 
  was 
  marked 
  

  

  11 
  Theses 
  for 
  the 
  degree 
  of 
  D. 
  V. 
  M. 
  from 
  the 
  New 
  York 
  State 
  Veterinary^ 
  

   College, 
  1897, 
  deposited 
  in 
  the 
  Cornell 
  University 
  Library. 
  

  

  