112 Missouri Agricultural Report. 



State Fair. A few days after the return of these animals one of 

 them, the Berkshire herd boar, died somewhat suddenly. The 

 herdsman, not suspecting an infectious disease, and thinking the 

 animal had probably been injured or over-heated, did not call my 

 attention to the matter for several hours after the animal had died ; 

 and it was impossible to give a positive diagnosis of the case, since 

 decomposition was well advanced before the examination was made. 

 My suspicions, however, were aroused that the case was one of 

 acute hog cholera. These "show hogs" had been unloaded in an 

 inclosure where the general farm herd* ran from time to time. 

 On November 8 a Duroc gilt that had been exposed with a number 

 of others upon these grounds, died during the day. The autopsy 

 showed highly injected lymph glands, enlarged and soft spleen, 

 great congestion of the mucous membrane of the intestines. Two 

 days later a Duroc sow, "Nokomis," that had been at the State 

 Fair died. The post-mortem examination of this animal gave evi- 

 dence of cholera. November 13 we inoculated 27 of the choicest 

 of the breeding herd with mixed serum supplied by Dr. Niles from 

 some of the Bureau's hyper-immunized hogs. In addition to this 

 we inoculated all of the surviving hogs that had been taken to the 

 State Fair — 5 head. One of these was very sick at the time, and 

 the other, her bed mate, was not eating well; making a total of 

 32 of the farm animals inoculated with the above material. We 

 gave to the large animals doses of 60 c. c. of the serum. This had 

 no good effect upon the sick sow, "Lucy Lee," nor her bed-mate, 

 "Early Rose." Both of these died from the disease. Two large 

 Duroc boars and one large Poland-China sow of the show herd 

 showed no signs of illness following the inoculation. They were not 

 taken from their pens which were adjoining the pen in which the 

 other animals died. They were also cared for by the same attend- 

 ant who had charge of the two sick sows. 



We lost out of the 27 of the general farm herd only one large 

 sow. This sow had been inoculated with only 40 c. c of the serum. 

 She was suckling 6 pigs at the time. These also died. A large 

 Duroc sow, suckling 11 pigs, but which received a larger dose, 50 

 c. c, and running in the same pen, showed no signs of the disease, 

 although all of her pigs died from the disease. Another sow in an 

 adjoining pen which had also received 50 c. c. of the serum, and 

 was suckling 6 pigs, showed no signs of the disease, although her 

 pigs died from cholera — the pigs of all three sows went back and 

 forth to infected pens near by. None of the other animals men- 

 tioned have shown any signs of illness. Thirteen of the choicest 



