310 Missouri Agricultural Report. 



bad and the animals were not sufficiently protected against the 

 winter storms. It is possible that a large number of the animals 

 would have recovered if they could have had dry, comfortable quar- 

 ters, so that pneumonic complications could have been avoided. 



Another instance is that of Mr. Bradford of Boone county, 

 who lost quite a number of his Berkshires. The disease appeared 

 during the worst part of the winter. The greater part of the 

 herd was infected at the time of vaccination. Sick ones as well 

 as those that were apparently healthy were vaccinated, as we 

 wished to test the curative effects of the vaccine as well as its 

 preventive properties, and to save as many of his valuable ani- 

 mals as possible. As has been our experience in other cases, 

 the greater part of those that showed well developed signs of sick- 

 ness succumbed to the disease ; and in this case, a number of others 

 which would no doubt have resisted the disease under better weath- 

 er conditions, also, died, either from the direct effects of the cholera 

 or from pneumonia induced by exposure to cold while in a weak- 

 ened condition. It was impossible under the conditions to pro- 

 vide dry, comfortable quarters for the large number of hogs in 

 his herd. Mr. Bradford holds the same opinion that we do, that 

 the unfavorable result was due to the fact that owing to his ab- 

 sence from home, the herd was not inoculated until most of the 

 hogs were already sick, and the exposure to the winter storms 

 caused many of the sick hogs to develop pneumonia. 



The unfavorable results in his own herd under the conditions 

 mentioned, has not caused him to lose faith in the efficacy of the 

 "serum" as a valuable "preventive," as he has knowledge of the 

 good results from the use of the serum in the infected herds of 

 some of his neighbors. 



I recall another case in Marion county, near Palmyra, where 

 we inocculated a lot of feeding hogs, on the farm of J. W. Mackey, 

 where quite a number of hogs had already died. (I found eighteen 

 head thrown in a ditch at the back of the farm. The partially de- 

 composed carcasses we at once disposed of by burning). Of the 

 remaining animals of the herd, two, which were severely ill, were 

 killed for diagnostic purposes. Both showed the acute hemorrhagic 

 type of cholera. The remaining 67 head were treated with serum; 

 some of these showed red blotches on the belly, or other signs of 

 the disease. How many more were already infected at the time 

 of inoculation it would be difficult to estimate. These hogs were 

 following cattle on "full feed," and the feed yards at this time were 

 deep in mud. The cold storms of January soon followed, and the 



