358 SUMMARY OF CURRENT RESEARCHES RELATING TO 



Cultures of B. coli gave this reaction after 24 hours, and similar 

 results were obtained by B. pseudo-dysenterm Flexner, and slightly by 

 B. typhosus after 20-25 days, but B. dysenterm Shiga-Kruse and B. 

 paratyphosus A and B gave negative results, as also did Pneumo-lacillus 

 Jriedlanderi and B. rhinosderinum ; StaphyJococcus aureus gave no re- 

 action, but Staph, alhus reacted positively ; the Vibrio choUrce group gave 

 positive reaction after 24 hours ; B. diphtheria reacted only slightly after 

 two weeks, whereas Hoffmann's pseudo-diphtheria bacillus gave a positive 

 reaction after 3 days. Many creatinin-producing organisms are also 

 vigorous acid producers. 



PfeiflPer's Bacillus in the Blood and Spleen of Influenza Patients.* 

 •O. Ghedini in 'l^^ cases of influenza found the specific bacillus in the 

 blood IS times (64 p.c.),and in 14 cases, in the spleen s times (57 p.c). 

 The bacillus was found in the spleen in all cases in which it occurred in 

 the blood. 



Streptococcus mucosus capsulatus.t — L. Scheuer has isolated a 

 variety of this organism from pus from the middle ear taken post-mortem 

 from a child dead from typhoid. It presented long cocci of the size of 

 Diploeoccus lanceolatus ; it stained badly by Gram's method ; formed 

 round convex finely granular yellow-brown colonies on agar ; on gelatin 

 the colonies are drop-like and transparent, later becoming opaque, the 

 medium not being liquefied ; milk is coagulated by fourth day ; broth is 

 clouded, and has a shining pellicle and abundant deposit ; no indol is 

 produced ; it is pathogenic for white mice ; it grows on blood media 

 both with and without haemolysis, either producing or not producing a 

 green colouring matter, and independently of its pathogenicity for man. 



Presence of Tubercles in the Lacteals of the Villi of the Intestine 

 in Tuberculous Infections. | — A. E. Metham fed a rabbit upon the 

 material obtained from the tuberculous mammary gland of a cow, and 

 killed the animal 38 days later. The intestinal lesions were especially 

 extensive in the neighbourhood of the ileocecal valve, and on the edge 

 of the lesion, where the villi were intact, the author found tubercles in 

 ^ihe lacteals. 



Studies in Tuberculosis.! — A. E. Metham inoculated a heifer in the 

 auricular vein with 5 c.cm. of a broth culture of avian tubercle obtained 

 from the liver of a turkey, the animal being previously submitted to the 

 tuberculin test with negative results. Twenty-one days later symptoms 

 of general infection supervened, and at the autopsy there was found 

 tuberculous broncho-pneumonia, and young tubercles in the liver and 

 spleen. The author also administered 20 c.cm. of the same culture to a 

 young bull by means of a stomach-pump. The symptoms in this case 

 were less marked, being shown chiefly by abnormal fluctuations of 

 temperature, and by a positive tuberculin reaction, which was obtained 

 within two months after inoculation. Tlie test applied four weeks later 

 gave a negative result, and the animal was killed. The autopsy showed 



* Centralbl. Bakt., Ite Abt. Orig., xliii. (1907) p. 407. 



+ Tom. cit., p. 332. 



X Proc. R. Irish Acad., xxvi. Sec. B (1907) p. 72. § Tom. cit., p. 67. 



