364 CHAPTER 39 



Jacob, F., and Wollman, E. L., "Genetic and Physical Determinations of Chromosomal 

 Segments in Escherichia Coli," Sympos. Soc. Exp. Biol., 12:75-92, 1958; reprinted 

 in Papers on Bacterial Genetics, Adelberg, E. A. (Ed ), Boston, Little, Brown, 1960, 



pp. 335-352. 



Jacob, F., and Wollman, E. L., Sexuality and the Genetics of Bacteria, 374 pp.. New York, 

 Academic Press, 1961. 



Taylor, A. L., and Adelberg, E. A., "Linkage Analysis with Very High Frequency Males 

 of Escherichia Coli," Genetics, 45:1233-1243, 1960. 



Taylor, A. L., and Adelberg, E. A., "Evidence for a Closed Linkage Group in Hfr Males 

 oi Escherichia coli K-12," Biochem. Biophys. Res. Commun., 5:400-404, 1961. 



Wollman, E. L., Jacob, F., and Hayes, W., "Conjugation and Genetic Recombination in 

 Escherichia coli K12," Cold Spr. Harb. Sympos. Quant. Biol., 21:141-162, 1956; 

 reprinted in Papers on Bacterial Genetics, Adelberg, E. A. (Ed.), Boston, Little, Brown, 

 1960, pp. 300-334. 



r 



Elie L. Wollman {left) and Francois Jacob (right) in 1961. 



QUESTIONS FOR DISCUSSION 



39.1. What events do you suppose occur between the time that donor DNA enters a female 

 conjugant and the time of appearance of a segregant which is haploid for a segment 

 of the donor DNA? 



39.2. What is the evidence that F can integrate in a chromosome? That it can deintegrate? 



39.3. What properties are attributable to F when this is integrated at a chromosomal locus? 



