more there are three papers on ageing as related to immune phenomena, as 

 well as one each on the regulation of Natural Killer Activity, on induction 

 of antibody formation in the newborn, and on alpha-fetoprotein induction of 

 immune-suppressive activity. Most papers are followed by discussions trans- 

 cribed from tape. The illustrations are confined to diagrams and graphs. 



METHODS 



Monographs 



45. 



J.C.DANIEL, Jr., ed. 1978. METHODS IN MAMMALIAN REPRODUCTION 



Acdemic Press, New York, etc. XVIII, 566 pp., 145 figs., 43 tabs., subject 



index. $ 39.50, £ 25.65 



Contents: 1. In vitro oocyte maturation, 2. The experimental production 

 of mammalian parthenogenetic embryos, 3. Manipulation of ploidy in the 

 mouse, 4. Methods for the high-resolution analysis of protein synthesis: 

 applications to studies of early mammalian development, 5. Microtechniques 

 with preimplantation embryos, 6. Production of chimeras by injecting cells 

 or tissue into the blastocyst, 7. Techniques for separating early embryonic 

 tissues, 8. Methods for the preservation of mammalian embryos by freezing, 

 9. Immunologic inhibition of development, 10. In vitro development of 

 whole mouse embryos beyond the implantation stage, 11. Implantation of 

 mouse blastocysts in vitro, 12. Advances in rabbit embryo culture, 13. 

 Advances in large mammal embryo culture, 14. Embryo transfer in large 

 domestic mammals, 15. Manipulation of marsupial embryos and pouch young, 

 16. Experimentation involving primate embryos, 17. Transplanting and ex- 

 planting organ primordia, 18. The regeneration of mammalian limbs and 

 limb tissues, 19. Pheromones, estrus, ovulation, and mating, 20. Experi- 

 mentally delayed implantation, 21. Laparoscopic research techniques in 

 mammalian embryology, 22. The use of amniocentesis in prenatal diagnosis, 

 23. Collection and analysis of female genital tract secretions, 24. Ex- 

 perimental approaches for elucidating the antifertility action of intrau- 

 terine devices in monkeys and rodents, 25. Surgical induction of endo- 

 metriosis 



Since this notice appears long after lengthy reviews have appeared in 

 other journals (Nature 276, 5685, 1978; Amer. Sci. 67, 3, 1979) we contend 

 ourselves with giving the complete table of contents and a few additional 

 remarks. 



It is obvious that this is one of those books that no mammalian embryo- 

 logist or experimental morphologist can do without. All chapters are written 

 by outstanding specialists and the book is a mine of information, and well 

 illustrated into the bargain. It is only marred by the fact that most bib- 

 liographies were already somewhat dated at the time of publication, and by 

 an inadequate index. 



HISTORY, BIOGRAPHIES, etc. (no entries) 



MISCELLANEOUS ITEMS ( no entries) 



184 



