PACIFIC AND BEERING'S STRAIT. 121 



finished his meal a most pleasing state of half intoxi- 

 cation had come on, so that he was just able to go to 

 his couch, where he enjoyed a sound and refreshing 

 sleep. 



" About the second or third week, the eyes became 

 suffused with blood, and the cuticle around them be- 

 gan, to scale, when the whole surface of the body 

 assumed the appearance above described. The first 

 dose is continued for a week or so, according to the 

 disease, and then gradually left off'. The skin clears 

 at the same time, and the whole system is highly be- 

 nefited. 



" I recommended the ava, and had an opportunity 

 of seeing the first effects upon a man affected with 

 chronic superficial ulceration, affecting the greater 

 part of the toes, and the anterior part of the soles of 

 the feet. The legs and feet were oedcmatous and 

 swelled ; the pain was very distressing, preventing any 

 sound repose, and not permitting him even to lie down 

 or bring them up, so as to be near a line horizontal 

 with the body. The ulcers were covered with a tough, 

 viscid, dark -coloured discharge that adhered to the 

 surface, and entirely concealed it. His frame was 

 emaciated, pulse quick and irritable, appetite gone, 

 tongue dry and reddish ; he had taken mercurial pre- 

 parations at two previous periods, as he said, with con- 

 siderable benefit ; but for want of the medicines it was 

 stopped, when the sores were nearly healed. He had 

 been, and I believe still was, addicted to drinking 

 spirituous liquors. The ava was given three times a 

 day with the same immediate effects as before-men. 

 tioned, and at the end of ten days the ulcers were 

 clean and healing. From the commencement of the 

 course he had been able to lie down, allowing his feet 



