the collagen fibres is also due to an orientated alignement of the dye 

 molécules, on the orientated AMP components in the fibre. Thus quantita- 

 tive data on metachromasia can be obtained from polarization microscopy. J 

 Différent chemical changes induced in the reactive side groups of the ' 

 substrates influenced in a spécifie manner the topochemical reactivity 

 of the collagen and elastic fibres as well as their enzymatic susceptibility 

 to the enzyme elastase. 



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