SOME ASPECTS OF CARBOHYDRATE METHABOLISM 

 OF THE TRANSITIONAL EPITHELIUM 



A. J. FRIEDENSTEIN 



Moscow, USSR 



I 



The transition al epithelium is osteogeneticalley active in the expérimental 

 conditions. This activity consists histochemically in the excrétion on the 

 epithelium of polysaccharides which signs the glycogen. It takes place at 

 the moment of the induction. At the normal differentiation the polysaccha- 

 rides of the transitional epithelium are in the reciprocal relations with the 

 unspecific alkaline phosphatase. The distribution of the phosphorylase in 

 such epithelium allows us to suppose that the phosphatase of this tissue 

 dephosphorylising the Cori's ester acts in the direction opposite to glyco- 

 gen synthesis. While dealing with différent ways of differentiation of the 

 transitional epithelium (keratinisation, mucin sécrétion) the glycogen is 

 seemingly utilised for the construction of acid mucopolysaccharides which 

 are associated with cystein or are parts of mucin. In the case of incom- 

 plète differentiation when the transitional epithelium is osteogenetically 

 active there appears the glycogen sécrétion directed under and over the 

 epithelial layer and the activity of phosphatase is decreased. This séc- 

 rétion as well as that of the epithelium of rénal coUecting tubes is streng- 

 thened under the influence of pituitrin. The product of this sécrétion 

 ("pelvin") contains glycogen and is specificaly histogenetically active. 

 In conclusion the rôle of polysaccharides of the urinary trarct in the histo- 

 genetical régulation is discussed. 



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