PRESENCE OF RIBONUCLEOPROTEINS 



IN MITOCHONDRIA OF DIFFERENT ANIMAL CELLS 



AND THEIR FUNCTIONAL IMPORTANCE 



A. L. SCHABADASCH 



The location of ribonucleic acid (RNA) or, more precisely, ribonucleopro- 

 teins (RNP) in cells, is considered usually in nucleolus and microsomes 

 (e.i. ergastoplasm). Our studies carried on with the hçlp of an improved 

 histo-chemical method, carefui control and sélective substratum removal 

 by ribonuclease digestion bave undoubtedly shown, that RNP are con- 

 tained in mitochondria of différent cells: nervous epithelial, mesenchymal, 

 blood and so on. 



RNP of différent organoids are characterised by différent isoelectrical 

 point (i.e.p.); typical i.e.p. zone, characteristic for RNP of mitochondria, 

 is the lowest on the pH scale (with normal cells), further go nucleolus 

 RNP and, finally, ergastoplasm. Certain catégories of cells (f.e. afférent 

 neurons, blood éléments and other) hâve also diffusai RNP with an iso- 

 point close to a free ribonucleic acid in their cytoplasm. 



RNP of mitochondria play an important rôle in the cell biology, they 

 regulate intermitochondrial ferments functioning conditions, participate in 

 transphosphorylation reactions and synthesis processes of ferments — typi- 

 cal and located in thèse organoids. Life activity of cells and expérimen- 

 tal influences are rapidly and accurately reflected through physico-chemi- 

 cal and morphological changes of RNP nf mitochondria which are recorded 

 by our cytochemical studies. 



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