with accumulation of proteins in the Kupffer cells and other macrophages 

 and in the cells of the convoluted proximal tabules of the kidney. 



2) Denaturated labeled sérum proteins decay faster in the circulation 

 and predominantly stored in the macrophages and kidney. 



3) Fluorescent dye solutions dissappeared rapidly from the circulation 

 and they were eliminated in the urine and trough the choledocus in the 

 small intestine. It was detected in very small amounts in the macrophages 

 and in the cells if convoluted proximal tubules of the kidney. 



4) Of ail labeled hormones used, which showed différents and sé- 

 lective sites of localization, only TSH was found in the connective tissue. 

 It decay rapidly in the circulation, appeared inmedialy attached to the 

 basai membrane of thyroid follicle and later in the connective tissue of 

 some ocular structures, in the interstitium of skeletal muscle, peri- 

 visceral adipose tissue and in the mast cells. Denaturated labeled TSH 

 decay faster in the circulation did not appeared in the thyroid gland but 

 could be seen with lesser intensity in the connective tissue structures. 

 Finally ail the labeled hormones were accumulated by macrophages of 

 the RES and by the cells of convoluted proximal tubules. 



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