ON HISTOCHEMISTRY OF EXTRAEMBRIONIC 



CONNECTIVE TISSUE 



IN PATHOLOGICAL CONDITIONS 



N. V. DONSKIHK, V. V. VINOGRADOV, M. Y. SUBBOTIN 



Novosibirsk Médical Institute 



I. Revealing the présence of acid mucopolysaccharides histochemically 

 is one of the most valuable and démonstrative methods of the study of 

 the pathology of the connective tissue of provisory organ showing early 

 morphological changes which are detected with difficulty. 



II. In nephropathy during pregnancy and in some inflammatory processés 

 in the placenta an increase of the amount of acid mucopolysaccharides 

 is seen in the connective tissue of the foetal part of the placenta. 



Very early and moreover, there are some changes in some fermentative 

 Systems. 



III. The development of hydramnion is accompanied by rapid accumula- 

 tion of highly polimeric acid mucopolysaccharides in the interstitial 

 layer of the amnion, that is in the amniochoriouic space. 



IV. Such increase in the accumulation of highly polymeric acid 

 mucopolysaccharides also takes place in Wharton jelly of the cord in 

 various pathological conditions when there is a possibility for infection 

 and toxins to pass from the mother to the foetus. 



V. In pathological conditions the accumulation of great amount of 

 acid mucopolysaccharides in the connective tissue of extraembryonic 

 organs can be regarded as a manifestation of the gênerai biological 

 protective reaction of the foetus. 



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