Fig. 5. Small field in a microsomal pellet (guinea pig) prepared like die specimen in 

 figure 4. 



A few microsomal vesicles appear in median {mv^), medial (mv 2 ), and lateral (mv 3 ) 

 section. The particles attached to the outer surface of the limiting membrane (arrows) 

 display their characteristic small size ( — 150 A) and high density. 



Fig. 6. Small field in a pellet obtained by differentially centrifuging a microsomal 

 suspension (like the one in figure 5) treated with Na deoxycholate (0.1 per cent, pH 7.2). 



The pellet consists of dense particles, — 150 A in diameter, which frequently occur in 

 chains (arrows) or in clusters. Their general morphology suggests that they are particles 

 detached from the microsomes as a result of the solubilization of the microsomal membrane 

 by deoxycholate. 



Both pellets were fixed and embedded like the specimen in figure 4. 

 Magnification: 120,000 for both figures. 



