no 



I. M. KLOTZ 



O 



in 



UJ 



O 



a. 

 -I 



? 



o 



llJ 



-6.0 



^ . etP^ . 1 ., 



LOG CoYE] pree 



Fig. 18. Comparison of binding of organic anion with organic cation by serum 

 albumin. 



Fig. 19 



form cross bonds with — C00~ side chains rather than with ^NH+. The result 

 would be that the ^NH+ side-chain, let us call it a lysine to visualize it more 

 concretely, would be relatively free. It would not be restricted in its configura- 

 tion. It would be able to come relatively close to organic-type side chains, say 

 leucines, which I have indicated by R (Fig. 19). The important thing is that 



