HARVEY M. PATT 



lens are decreased as cataract develops, this is a delayed and not an immedi- 

 ate effect of X-irradiation^*. Evidence for a post-irradiation effect of 

 p-mercaptoethylamine in the liver shielded animal, perhaps suggestive of a 

 biochemical locus, is, at best, conflicting^^' 2^. No doubt, various bio- 

 chemical and physiological states can profoundly affect radio-sensitivity. 

 Protection of mammalian systems with chemicals such as cysteine and 

 P-mercaptoethylamine appears, however, from the preponderance of circum- 

 stantial evidence, to be related mainly to an effect on energy transfer 

 mechanisms rather than to a specific effect on one or another biological 

 determinant of injury or recovery. 



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