THE MODIFICATION OF THE RADIATION RESPONSE BY SHIELDING PROCEDURES 



and Aliss M. IVinsborough. We are very indebted to Professor W. V. Mayneord 

 for his constant support and encouragement. 



The financial help of the Medical Research Council and of the British Empire 

 Cancer Campaign is gratefully acknowledged. 



REFERENCES 



1 Lamerton, L. F.. Elson, L. A., Harriss, Eileen B. and Christensen, W. R. Brit. 

 J. Radiol. 1953, 26 510 and 568. 



2 Lamerton, L. F. and Baxter, C. F. ' An Experimental Study of Radiation- 

 induced Anaemia with Reference to Shielding Procedures and Platelet Changes,' 

 ibid., in press. 



^ Lamerton, L. F., Belcher, E. H. and Harriss, Eileen B. Radioisotope Conference, 



1954, Volume L London, Butterworths, 1954. 

 * Baxter, C. F., Belcher, E. H., Harriss, Eileen B. and Lamerton, L. F. 



' Anaemia and Erythropoiesis in the Irradiated Rat. An Experimental Study with 



particular reference to Techniques involving Radioactive Iron,' Brit. J. Haematol., 



in press. 

 ^Belcher, E. H., Gilbert, I. G. F. and Lamerton, L. F. Brit. J. Radiol, 1954, 



27 387. 

 ^ Jacobson, L. O. Cancer Res. 1952, 12 315. 



DLSCUSSION 



B. JoLLEs : In connection with the findings described by Lamerton and with 

 what has been said it is worth recording that Swift, Taketa and Bond* in their 

 experiments with regionally fractionated X-irradiation (divided exposure) have 

 shown among other things that the degree of protection obtained in rats appeared 

 similar, irrespective of the order in which the two portions of the body were irradiated 

 or of the time interval (10 or 120 minutes) allowed between exposures. The matter 

 is complicated further by the fact that there are several recovery factors with different 

 mechanisms of action and time lags. In investigations on the skin radiation reaction 

 recovery factors I have noted that only some of the reaction phases are influenced by 

 the amount of normal surrounding tissue. 



* Swift, Taketa and Bond. Radiation Res. 1954, 1 241. 



140 



