86 NEUTROX EFFECTS OX ANIMALS 



The substrate was again changed, this time to edestin and cysteine at a 

 pH of 3.95, and both sonicized and ordinary samples of bone marrow ex- 

 tracts were examined. One series of tests was run as long as 7 days at 

 37°C'. but no increase in reaction values was obtained. 



A sample of bone marrow from a dog which had been subjected to neu- 

 tron radiation was examined with this particular substrate, but the values 

 were as negligible as those found on the bone marrow of normal animals. 



SUMMARY 



Xo evidence of proteolytic enzymes was found in either sonicized or 

 non-sonicized samples of bone marrow from normal animals. A sample 

 from an irradiated dog was also negati^•e. 



REFERENCES 



(1) Lixderstr0m-Lang, K., and Holter, H., Compt. rend. Lab. Carlsberg, 19, No. 



4 (1931). 



(2) Weil, L., axd Jennings, R. K., J. Biol. Chem., 139, 421 (1941). 



(.3) Chambers, L. A., and Flosdorf, E. W., Proc. Soc. Exptl. Biol. Med., 34, G3I 

 (1936). 



