NEUTRON EFFECTS ON ANIMALS 



29 



perimental work was to stud\' the effects of a relatively wide range of neu- 

 tron doses on the general condition of the rats and also on such specific 

 changes in the blood as might occur. 



For the higher neutron doses, four groups of six male rats each were 

 irradiated with one to four 60-n doses on consecutive days for accumulative 

 doses of GO n, 120 n, ISO n and 240 n, respectively. Four other groups of 



TABLE I 



Radiation Data for All Experiments 



* All irradiation was carried out on consecutive days with the e.xception that 

 those receiving twelve 10-n doses were irradiated in 14 daj^s with no irradiation on 

 the third and fourth day, and those rats receiving repeated 1.8 n were irradiated 

 daily except Sundays. 



t The box number refers to the corresponding data given by Enns et al. (7) for 

 the procedure of irradiation of experimental animals. 



six male rats each were irradiated on a single daj^ with closes of 17.5 n, 

 32.5 n, 47.5 n and G2.5 n, respectively. Observations on these animals 

 were limited primarily to gross pathology, and to changes in body weight 

 and total leukocyte counts. Xo histological study was made of any 

 tissues from the rats in this series of doses. Blood hemoglobin deter- 

 minations by the acid-hematin method were made on the rats receiving 

 17.5 n to 62.5 n. However, since these values showed no significant differ- 

 ences between irradiated and non-irradiated animals, these data are not 

 reported in detail. In addition, when it was noted in the 60-n and 120-n 



