NEUTRON EFFECTS ON ANIMALS 



1G3 



gravity of the plasma decreased slightly at first, then increased slightly 

 above the pre-irradiation level (Table I). 



MM 



^?~^0~~o^_ 



20 



40 



60 



80 



100 



o — o 



\, 



\. 



8 



16 



20 



12 



HOURS 



Fig. 2. Effect of 400 n on the blood sedimentation rate of dogs 

 tion. A 3 days after irradiation. D 6 days after irradiation. 



24 



O Pre-irradia- 



No effect on the fragility of the erythrocytes was found. 



Blood Chemistry. Animals were fasted for 24 hours before samples of 

 blood were taken. Determinations of the blood glucose (6), blood chloride 

 (7), serum calcium (8), inorganic phosphorus (9), plasma total nitrogen 

 and plasma non-protein nitrogen (10, 11) were made prior to irradiation 

 and 3, 6 and 8 days after completion of irradiation. 



Chloride values remained relatively constant (Table II). Cducose con- 

 centrations increased slightly but consistently. From dog ^ 1, the last 

 sample of blood was taken only 10 or 15 minutes before death. The glucose 

 concentration for this sample was 72 per cent, higher than the initial aver- 

 age for the 4 dogs. 



The serum calcium increase averaged 20 per cent, in the six days follow- 

 ing completion of irradiation. The inorganic phosphorus increased ap- 

 proximately 43 per cent. Total nitrogen of the plasma increased approx- 

 imately 17 per cent, in six days, while the average decrease of non-protein 

 nitrogen was 17.7 per cent. 



Gross Pathological Findings. See table on page 104. 



Histopathological Findings (By Douglas AI . Gray) . See table on page 166. 



