Nucleic Acids and Nucleoproteins 69 



It has been found by my colleagues Dr. Hunter and Dr. 

 Crathorn, that with Staphylococcus aureus the effect of a 

 series of nitrogen mustards in inhibiting the incorporation of 

 an amino acid under conditions of starvation runs parallel to 

 their effects on tumour inhibition (Table III, Hunter and 

 Crathorn, 1956, unpublished experiments). There are thus 

 reasonable grounds for expecting that the reaction of the 

 nitrogen mustards with nucleic acids in the cell will have 

 metabolic consequences and will also affect the genie charac- 

 teristics. 



Acknowledgement 



I am indebted to my colleagues Drs. A. R. Crathorn, P. Cohn, G. D. 

 Hunter and D. M. Phillips for permitting me to quote unpublished 

 results. 



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