CONTENTS 



PAGE 



Chairman's opening remarks 



by A. Haddow ........ 1 



Cytoplasmic and nuclear structure in relation to metabolic 

 activities 



by J. Brachet ........ 3 



Discussion: Bracket, Butler, Davidson, Gray, Holmes, 



Howard, Roller, Popjak ...... 20 



The effects of ionizing radiations on enzymes in vitro 



by W. M. Dale 25 



Discussion: Alexander, Butler, Dale, Forssberg, Popjak 34 



The activity of enzymes and coenzymes in irradiated 

 tissues 



by Antoinette Pirie ...... 38 



Discussion: Alexander, Alper, Van Bekkum, Butler, 



Gray, Lajtha, Latarjet, Pirie ..... 56 



Effects of X-rays and radiomimetic agents on nucleic 

 acids and nucleoproteins 



by J. A. V. Butler ....... 59 



Discussion: Alexander, Alper, Butler, Forssberg, Gray, 

 Haddow, de Hevesy, Hollaender, Roller, Lajtha, 

 Latarjet, Mitchell, Spiegelman .... 70 



Oxidative phosphorylation in some radiosensitive tissues 

 after irradiation 



by D. W. VAN Bekkum . " . . . . .77 



Discussion: Van Bekkum, Brachet, de Hevesy, Holmes, 



Howard, Roller, Laser, Loutit, Mitchell, Popjak . 89 



The effects of extraneous agents on cell metabolism 



by H. A. Rrebs ....... 92 



Discussion: Alexander, Brachet, Cohn, Dale, Haddow, 



Rrebs, Lajtha, Zamecnik . . . . . .103 



vii 



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