234 



Barbara E. Holmes 



Table IV 



Effect of Radiation on Glucose Oxidation by Slices of Regenerating 



AND Normal Liver 



* statistical comparison shows that the mean of group A is significantly higher than that of 

 group B (P = 0-02) and that of C (P < 01). 

 Rats were killed 15^ to 16 hours after X-irradiation. 



Irradiation dose was 600 r except in experiments 1 and 2 where the dose was 450 r. Partial 

 hepatectomy was carried out immediately after irradiation. 



more direct connection between inhibition of growth and 

 inhibition of DNA synthesis by irradiation. 



Dr. Dittrich, of Dr. Schubert's laboratory in Hamburg, 

 was kind enough to send a strain of Ehrhch mouse carcinoma 

 which had been made radioresistant by irradiation at a num- 

 ber of successive passages, as described by Dittrich, Hohne 

 and Schubert (1956). This tumour was grown as a solid 

 tumour in the leg of an inbred strain of white mice and was 

 compared with a normally sensitive strain of the same tumour 

 grown in the same strain of mice. Tumours inoculated on the 

 same day and grown to the same size were used, and ^^P was 



