DNA AND Effects of Radiation and Peroxides 297 



Brinton and R. Monier, who obtained some of the most significant 

 results on bacteriophage, bacteria and pepsin; Dr. H. Ephrussi-Taylor 

 and Miss N. Cherrier, who participated in the experiments on the 

 transforming agent ; Mr. P. Morenne and Miss G. Hiernaux for their 

 excellent technical assistance; Dr. J, Jagger and Mrs. P. Monnot for 

 their help in preparing the English text. 



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DISCUSSION 



Butler: Do Stent's experiments, in which he produced a great many 

 disruptions of nucleotide threads without losing the activity, fit in well 

 with yours ? 



Latarjet: Yes. 



Spiegelman: It is remarkable that this estimation of the order of 

 magnitude of a tenth fits in with two quite independent experiments. 

 One is Benzer's whose gene size is down tb 10 nucleotide pairs, and the 

 other is Stent's experiment where with ^^p decay about one out of ten 

 leads to a lethal event. 



Gray: Another way of putting what has been said is that in the 

 target the volume is not necessarily aggregated. A second point is that 

 the first part of the curve seems to me to indicate that one in ten of the 

 particles are not subject to this inhibition of penetration into the 

 bacillus. In some way they must be different from the other nine, since 

 they are not appreciably inactivated by the doses which you used. 



Latarjet: They behave differently after irradiation. 



