316 



Subject Index 



Nucleic acids, and amino acid in- 

 corporation, 174-182 

 and effects of X-rays and radio- 

 mimetic agents, 59-69 

 biological functions of, 174 

 digestion on, 178-179 

 permeability of cells to, 184 

 purity of preparations, 183-184 

 radiation on mixtures of, 304 

 structure, 59-60 

 Nucleic acid synthesis, and rate 

 limiting reactions, 105 

 and viability of cells, 132 

 metals on, 184 

 relation to protein, 172 

 Nucleolus, role in cell metabolism, 4, 



6, 12, 17 

 Nucleoproteins, radiation on, 269 

 radiosensitivity of, 72-73 

 structure, 59 



X-rays and radiomimetic agents 

 on, 59-69 

 Nucleus, role in cell metabolism, 

 3-20 

 transfer of, between two species, 23 

 Organic peroxides, effect on viral 

 and bacterial functions, 275- 

 297 

 inactivation of bacteria by, 278- 

 280 

 of bacteria-bacteriophage com- 

 plexes by, 283-284 

 of bacteriophage by, 280-283 

 of pepsin by, 288-289 

 of Pneufnococciis-tTansforming 

 principle by, 290-291 

 influence of light on effect of, 



280 

 mutagenic effects of, 287-288 

 posteffect on bacteriophage, 

 284-286 

 Orotic acid incorporation, in de- 

 oxyribonucleic acid, 196 

 in ribonucleic acid, 171 

 Osmotic control in retinal tissue, 50 

 Oxidative phosphorylation, and 

 adenosine triphosphatase ac- 

 tivity, 86 

 and pacemakers, 96 

 and radiation dose, 81-82 

 and rate of oxygen consumption, 



96 

 and the " Pasteur effect ",94 

 and tissue specificity of radiation 

 effect, 83-84 



Oxidative phosphorylation 



during radiation, 91 



inhibition by chemical mutagens, 



245, 248-250 

 in radiosensitive tissues, 77-89 

 relation to nuclear metabolism, 



82 

 relation to cytochrome c, 86 

 site of, 3 

 Oxine, see 8 -hydroxy quinoline 

 Oxygen consumption, control of 

 rate of, 96 

 in isolated nuclei, 3 

 radiation on, 41 

 Oxygen effect, 106-115 



and deoxyribonucleic acid in- 

 activation, 208 

 and metabolic activity of the 



cell, 111-112 

 and mitochondria, 88 

 and radiation damage, 109 

 and respiratory poisons, 108 

 and sensitization, 28 

 in chromosomal aberrations, 



242-243 

 in fresh yeast, 112 

 in low-nitrogen yeast, 112 

 in relation to protection, 113- 



114 

 on enzyme activity, 114-115 

 on Esch. coll B, 116 

 on growth of Sarcina lutea, 108- 



109 

 on metabolism (respiration and 

 glycolysis) of Esch. coli, 110- 

 111 

 on nucleoproteins, 73 

 on Pnetimococcus-transiorming 



principle, 295 

 on rate of reproduction of 

 Sarcina lutea, 108 

 Oxygen uptake, effect of radiation 

 on, 43, 81, 82 

 in presence of glucose, 110 

 Pacemaker reactions, 92-93, 95, 



96, 104 

 Parabiosis, and recovery after ir- 

 radiation, 140 

 Paramecia, induced mutagenic effects 



in, 287-288 

 Particulate cell constituents and 



protein synthesis, 162-168 

 Part- inactivation of bacteriophage, 



286-287 

 " Pasteur effect", 94 



