282 G. M. FRANK AND A. D. SNEZHKO 



of their inter-relation reqnires the development of procednres of a 

 strictly sj^atial matching and observation of these phenomena. 



When discussing the meaning of these periodical processes and their 

 damage by radiation we can but voice some speculations. 



The thesis that perfect mechanisms of self-regnlation must exist in 

 the chemical activity of living cells is irrefutable. Self-regulating 

 mechanisms must be flexible and. in the terms of modern techniques, 

 must at any given moment provide the adjustment of all the running 

 processes to the most advantageous working regime. 



In respect of most chemical processes it would be very unlikely to 

 suppose that they maintain either their level or their rate, changing 

 smoothly so that the curve of these changes in time will be of a monoton- 

 ous character. 



Any regulator has tolerance, and the regulatory process fluctuates 

 between both the upper and the lower limits. It is just according to 

 this principle of relay or impulse regulation that the most perfect, 

 automatically working, self-regulating and self-adjusting systems are 

 constructed. 



This type of regulation for which modern techniques have only re- 

 cently been available is supposed to have been worked out millions of 

 years ago in the process of evolution. The level of oxygen processes, 

 which is of dentate character, may witness this kinetic regulatory 

 process in its outward appearance. 



What are the possible mechanisms for such a regulation? We need 

 another one, even though somewhat fantastic assumptions are required. 

 The existence of a continuous relationship between the structural 

 organization of cells at any given moment and kinetic exchange pro- 

 cesses is beyond any doubt. This viewpoint is confirmed by all the recent 

 findings when the problem of the intermolecular architectonics of living 

 has become so developed and received such a new significance; when 

 the dynamic aspects of morphology are being developed and the con- 

 tinuous structural mobility at any level of the organization of living 

 organisms is being more and more demonstrated. 



For this the specific structural and ultrastructural organization not 

 only provides a co-ordinated running of chemical processes but on the 

 contrary this co-ordinated running maintains the very structural 

 organization. On the cessation of vital activity a disorder between 

 structural organization and the interacting ensemble of chemical pro- 

 cesses takes place. 



This inter-relation is of a typical character of reverse relation, i.e. of 

 interaction absolutely necessary for the construction of any self- 

 regulating system. 



