RADIATION IN PRENATAL DEVELOPMENT 



895 



to Bagg's syndrome) , which was first noticeable externally on the fourth 

 day (Lacassagne, Lavedan, and Leobardy, 1922). Coagulation time was 

 progressively decreased, starting with the seventh day, and platelets were 

 absent. Lacassagne and Lavedan (1922) report blood counts on pre- 



,•-5 



IRRADIATED 

 RABBITS 



CONTROLS 



D D 



RED BLOOD CORPUSCLES 

 POLYNUCLEAR WHITE CELLS 

 MONONUCLEAR WHITE CELLS 



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if) 



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o 



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 z> 

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29 30 31 



— i— 

 4 



— i — 

 8 



>A- 

 9 



10, 



POSTNATAL 



POSTCONCEPTION 



AGE, DAYS 

 Fig. 13-8. Average counts of red blood corpuscles polynuclear white cells, and 

 mononuclear white cells in rabbits irradiated in utero 2-3 days before term. 

 Counts were begun following irradiation on day 29 postconception and were con- 

 tinued daily until death. (Graphs constructed from data presented by Lacassagne and 

 Lavedan.) 



sumably the same group of animals. Figure 13-8 was constructed from 

 their data. The red count of irradiated animals is normal until the 

 fourth day after birth when it takes a sharp drop and continues to fall. 

 The effect on total white count is more immediate, consisting of almost 



