602 RADIATION BIOLOGY 



constitution and manner of reaction of the genetic material. This has 

 been illustrated, for example, in the studies on the modification of the 

 general biological effects by various accessory agents, in cases where it 

 was later found that similar influences were exerted on mutagenesis. 



Out of the welter of complicated and sometimes apparently contra- 

 dictory facts now emerging in the studies on radiobiology and radio- 

 mimetic agents and on mutagenesis occasioned by radiation and by these 

 agents, more than suggestive signs of order are beginning to appear. 

 They encourage a feeling of optimism with regard to the further progress 

 of the attack, -provided that the investigator is left with as much freedom 

 as possible to follow leads as they appear rather than having to confine 

 himself by a rigid application of the "project system" of investigation. 



REFERENCES 



(Information concerning the availability of government documents indicated by an 

 asterisk can be obtained from the Office of Technical Services, Department of 



Commerce, Washington, D.C.) 



Alberti, W., and G. Politzer (1923) tJber den Einfluss der Rontgenstrahlen auf die 

 Zellteilung. I. Arch, mikroskop. Anat. u. Entwicklungsmech., 100: 83-109. 



and (1924) Uber den Einfluss der Rontgenstrahlen auf die Zell- 

 teilung. II. Arch, mikroskop. Anat. u. Entwicklungsmech., 103: 284-307. 



Allen, A. O. (1948) Radiation chemistry of aqueous solutions. J. Phys. & Colloid 



Chem., 52: 479-490. 

 Altenburg, E. (1930) The effect of ultraviolet radiation on mutation. Anat. 



Record, 47: 383. 



(1931) Genetic effects of ultraviolet radiation. Anat. Record, 51 (Suppl.): 



108-109. 



(1933) The production of mutations by ultra-violet light. Science, 78: 587. 



(1934) The artificial production of mutations by ultra-violet light. Am. 



Naturalist, 68: 491-507. 



(1936a) Eggs for ultra-violet treatment. Drosophila Info. Serv., 6: 22. 



(1936b) The production of mutations by the polar cap method of treatment. 



Biol. Zhur., 5: 27-34. 



-, J. Bergendahl, and L. S. Altenburg (1952) The non-effect of intensity in the 



mutagenesis of ultraviolet within a nineteen-fold range in Drosophila. Genetics, 



37: 554-557. 

 Altenburg, L., and E. Altenburg (1952) The lowering of the mutagenic effectiveness 



of ultraviolet by photoreactivating light in Drosophila. Genetics, 37: 545-553. 

 , , and R. Baker (1952) Evidence indicating that the mutation rate 



induced in Drosophila by low doses of ultraviolet light is an exponential function 



of the dose. Genetics, 37: 558-561. 



-, H. U. Meyer, and H. J. MuUer (1949) The lack of proportionality 



of mutations recovered to dose of ultra-violet administered to the polar cap of 



Drosophila. Records Genet. Soc. Am., 18: 75; Genetics, 35: 95 (1950) (abstract). 

 Amato, A. (1911) tJber die Wirkung der Rontgenstrahlen auf in Karyokinese 



begriffene Zellen. Z. Rontgenkunde Radiumforsch., 13: 1-14. 

 Anderson, E. H. (1951) The effects of oxygen on mutation induction by X-rays. 



Proc. Natl. Acad. Sci. U.S., 37: 340-349. 



