EXPERIMENTS WITH CYTOST 99 



The protocols following are representative of many 

 of the author's observations. 



Cat No. XII. Male. 



March 1,1919. 2 P.M. Temperature 40°. 5 cc. of ether injected 

 subcutaneously on right side. No immediate effects although 

 animal appears stupid. 



3 P.M. Temperature 37°. Lying down, moaning. Remained 

 this way for ^ hour, then recovered. 



March 4. 5 cc. ether injected on left side. In 10 minutes com- 

 menced to stagger. 



March 8. Thin and weak. 5 cc. ether injected on right side. 



March 13. 5 cc. ether injected on left side. Stupor, then coma. 



March 14. Found dead. 



Autopsy: Liver and spleen, enlarged and congested; omen- 

 tum, sclerosed, hardened; stomach and duodenum, congested, 

 stained with bile ; lungs, red, solid, pneumonic ; brain, normal. 



Cat No. XVII. Male 



Feb. 28, 1919. 2:50 P.M. Temperature 40°. Injected 10 cc. al- 

 cohol in each side. 

 3:00 P.M. Temperature 38°. 



March 4. Injected 10 cc. of alcohol on each side. 



April 17. Injected 10 cc. of alcohol on each side. Staggered about 

 for ten minutes, then became comatose, remaining so for 8 hours. 



April 18. Found dead. 



Autopsy: Pneumonic spots, marked congestion; stomach 

 and duodenum, congested, hemorrhagic; liver, very congested, 

 omentum hardened ; spleen enlarged, infarct ; kidneys, marked 

 congestion; brain, normal. 



In such experiments, objection may be raised 

 against the relatively large quantities of the reagents 

 injected into the animals. In order to obviate this, the 

 following procedure was devised. The animal's leg 



