96 THE ACTION OF THE LIVING CELL 



Autopsy : stomach, few hemorrhagic spots. Duodenum, con- 

 gested and atrophied ; spleen, enlarged, infracts ; liver, very 

 hemorrhagic; lungs, characteristic lesions; kidneys, congested. 



No. 86 

 Female cat. JVeight 2900 gms. 



April 8, 1920. 1 cc. injected intraperitoneally and 1 cc. subcu- 

 taneously. Temperature 101°. 



April 13. Similar injections. Temperature 101°. Animal appears 

 to be weak. 



April 18. Similar injections. Temperature 100°. 



April 19. Died. 



Autopsy: Stomach and duodenum show erosions and what 

 appear to be breaking doAvn ulcers; liver, very hemorrhagic; 

 spleen, enlarged ; kidneys, congested ; lungs, characteristic ap- 

 pearance. 



Results similar to the above have been obtained a 

 great many times. Occasionally, however, a cat was 

 encountered which was apparently capable of toler- 

 ating such injections of cytost for a much longer pe- 

 riod of time. Such animals however eventually suc- 

 cumb to the long-continued action of cytost, and when 

 autopsied are found to exhibit degenerative tissue 

 changes similar to those recorded in the preceding 

 protocols. For example, consider cat No. 89. 



No. 89 

 Castrated male cat. Weight 3250 grams. 



April 26, 1920. Injected 1 cc. intraperitoneally and 1 cc. subcu- 

 taneously. This was repeated on each of the following dates 

 unless otherwise noted. 



May 



