38 THE ACTION OF THE LIVING CELL 



chloroform or ether anesthesia for periods of from 

 three to six hours. From twelve to twenty-four hours 

 after the removal of the anesthetic, the animals uni- 

 formly exhibited the symptoms of shock, such as sub- 

 normal temperature and blood pressure, and pale 

 tongue and cold surface; frequently death ensued. At 

 the time these experiments were published the author 

 commented that: "The conclusions that can be drawn 

 from the details of the experiments made on animals 

 under chloroform or ether are that where shock is 

 produced it does not materially differ from the shock 

 that results from trauma. The most constant patho- 

 logic factor is failure of circulation, and this is espe- 

 cially expressed in splanchnic congestion." (Turck, 

 1903b.) 



When blood serum obtained from dogs which had 

 been subjected to anesthesia the day previous was in- 

 jected intravenously into normal dogs, the latter de- 

 veloped symptoms of shock. This result shows that 

 in shock produced by anesthesia cytost is liberated in 

 the blood in much the same fashion as in shock induced 

 by other means. 



The following protocols taken from the paper 

 above referred to clearly show the nature of this re- 

 action. 



• 



Experiment 16. Mongrel, placed under ether anesthesia; pres- 

 sure 140; kymographic tracings. Ether. Temperature, 41. In- 

 jected 90 cc. serum from dog which had been under anesthesia for 

 5 hrs. The serum had been removed the following day. Blood pres- 

 sure fell 80-70 ; forty-five minutes, temperature 36° C. Coagulation 

 marked, interfering with further blood pressure records. Anes- 

 thesia removed ; animal placed in warm location ; temperature fol- 

 lowing day 37° C. After three days, animal still showed symptoms 



