110 THE ACTION OF THE LIVING CELL 



hair, sclerotic changes in the marginal vessels of the 

 ears, and hemorrhagic zones at the junction of the 

 gums and teeth. 



Cat No. 114 (Abstract of Protocol) 



Young female, white with black spots 



Nov. 9, 1920. Weight, 1750 gms. Injected intraperitoneally 1 cc. 

 of cytost extract prepared by boiling 10 gms. of autolyzed cat 

 heart muscle with 50 cc. of water and evaporating to 25 cc. 



Nov. 11, 12, 13. Similar injection. Sneezes, discharge from eyes. 

 These symptoms subsided by the 20th. 



Nov. 13-21. Similar daily injections. 



Dec. 7. Weight 2015 gms., good appetite but has appearance and 

 actions of animal about to break down. Hence allowed a 

 month for recovery. 



Dec. 13. Weight, 1835 gms. 



Jan. 9, 1921. Weight, 2270 gms. Appeared normal hence in- 

 jections commenced again. Used 1 :25 extract of autolyzed cat 

 muscle. Injected 1 cc. subcutaneously each day from Jan. 9, 

 1921, until Feb. 17. During this time the cat progressively 

 gained in weight. 



Feb. 17. Weight, 2640 gms. 



Feb. 18. In heat, assaulted by tomcat. 



Feb. 19-26. Daily subcutaneous injections of 1 cc. 



Feb. 27. Weight, 2520 gms. Blood vessels around margin of ear 

 appeared sclerotic. Hemorrhagic zone at margin of gums. In- 

 dicates vascular and nephritic changes. Daily injections of 1 cc. 

 continued until 



April 7. Aborted two kittens about 4 weeks gone. No injection. 



April 8. Aborted another kitten. No injection. 



April 10-May 26. Daily injections but no noteworthy changes. 

 Weight, 2420 gms. Apparently the cytost extracts used were 

 too weak. Hence changed to muscle extracts made by ex- 

 tracting 10 gm. portions of autolyzed muscle with 10 cc. of 

 water. 1 cc. of the extract injected daily until 



July 7. Unable to climb or jump, very sensitive, resents handling, 

 poor appetite, receding gums and extensive dental caries. Daily 

 injections continued till 



