90 THE ACTION OF THE LIVING CELL 



age which becomes evident following severe burns 

 belongs in this category. 



In order to study such conditions, areas on the backs 

 or buttocks of animals were anesthetized by injections 

 of novocaine. The muscle and skin were then grasped 

 by clamps and burned to char by the application of 

 a white-hot branding iron for a few moments. A few 

 hours after such treatment the animals passed into 

 shock (Turck, 1918) . In Table VII are recorded the 

 time of the onset of shock following such burns. 



TABLE VII 



The crisp charred tissue was dissected from the 

 burned areas of such animals and pulverized. One- 

 gram portions of this material were then extracted 

 with 10 cc. of water and filtered. This extract was then 

 injected intravenously into normal homologous ani- 

 mals, 1 cc. portions being used for cats and rabbits, 

 and 2 cc. portions for the dogs. By this means a much 



