NATURAL RESISTANCE AND FATIGUE 163 



substance from the active muscles. By proper train- 

 ing, however, such a resistance is developed; for the 

 gradual liberation of small quantities of cytost by ap- 

 propriate exercise may be considered to stimulate the 

 formation of anticytost and thus endow the individual 

 with an appropriate mechanism for combating fa- 

 tigue. 



On this basis one is enabled to account for the fre- 

 quently remarked fact that oftentimes individuals of 

 perfect muscular development are less able to with- 

 stand certain types of physical exertion than are those 

 of distinctly less prowess. On the basis of what has 

 been said above, distinct muscular development as 

 seen in ex-athletes and captive wild animals depends 

 upon past performances which have stimulated the 

 development of the muscles, while resistance to fa- 

 tigue depends upon the immediate presence of anti- 

 cytost in sufficient quantity. Thus, an ex-athlete or 

 captive animal may, due to forced inaction, fail to 

 stimulate the formation of sufficient anticytost to over- 

 come the fatiguing effects of what otherwise might be 

 regarded as a relatively simple physical task. From 

 these considerations it is seen that there is not neces- 

 sarily a correlation between physical development 

 and resistance to fatigue. 



Before leaving this discussion, one more factor 

 must be considered: the results attending complete 

 physical inaction. Such results are well seen in indi- 

 viduals afflicted with some pathology which has 

 caused a degeneration of some portion of the motor 

 nerve paths — such, for example, as infantile paralysis, 

 or, in experimental animals, section of the motor 

 nerves passing to a limb. In consequence of such in- 



