NATURE OF CYTOST 243 



brings about an intensification of the action of cytost 

 already present in much the same fashion as that in 

 which Weaver and his associates have found the ash 

 to intensify the localized action of histamine. 



While this is an hypothesis vs^hich merits serious 

 consideration, the author feels that it is incorrect. 

 This objection is based upon the observation previ- 

 ously mentioned that ignition of a tissue at 700° C. 

 leads to the formation of a virtually non-toxic ash. 

 Such an ash must contain all the inorganic substances 

 which were present in the original tissue. Conse- 

 quently the toxicity of the ash obtained at lower tem- 

 peratures cannot be due solely to the augmenting 

 effects of such inorganic substances upon the cytost al- 

 ready present in the tissues of the experimental animal. 

 It is obvious that further experimentation will be 

 necessary to settle this point definitely. 



