458 First European Journey 



studies continuing and more cancers resulting, Smith read his 

 " lucid papers ... as fascinating as a romance," " By these inves- 

 tigations," Fibiger claimed in 1913, " carcinomatous tumours 

 giving rise to metastases were produced experimentally for the 

 first time, and the hypothesis put forward by Borrel and Haaland 

 was thus verified, as it has now been proved that nematodes play 

 a causal part in the development of cancer in rats." 



In 1912 in his address, " Le Cancer," ^^ before the International 

 Congress of Comparative Pathology, Borrell considered in support 

 of the parasitic hypothesis of cancer his own researches and con- 

 clusions, Rous's transmission of sarcoma in chickens by direct 

 inoculation with a cell-free or virus filtrate, and Jensen's con- 

 firmatory work of Smith's main conclusions of the comparison 

 of crown gall and malignant tumor formation in animals. The 

 next year Smith, in an address ^" before the seventeenth Inter- 

 national Congress of Medicine, would quote from Borrel's esti- 

 mate of his work and the intimation that he. Smith, had been 

 " the first one to produce a cancer by inoculation with pure 

 cultures of a micro-organism, and the first one to furnish proof 

 that it is actually a symbiosis." 



On November 23, 1912, Dr. Louis B. Wilson, director of the 

 Laboratories of the Mayo Clinic, invited Smith, on the behalf of 

 a committee, " to have at the Scientific Exhibit of the American 

 Medical Association in Minneapolis next June as large a number 

 as possible of pieces of research which shall be demonstrated by 

 the men who have done the work. We will have," he explained, 



the exclusive use of the new building of the Department of Anatomy, 

 which contains an amphitheatre and two large lecture rooms besides 

 numerous small rooms. We shall place the exhibits around in the smaller 

 rooms (all of which are connected) and provide for a regular program 

 of lantern slide demonstrations in the lecture rooms. Last year at Atlantic 

 City we did something of the sort and the men who were on the program 

 were much pleased with it. Several of them, in fact, said it was the best 

 opportunity they had had to present their material to the sort of an audience 

 that they most desired to reach. Besides general research, I am particularly 

 interested in that on cancer and should like if possible to have an " exhibit 



^^ See an excerpt of three paragraphs from Borrel's paper in Smith's address, 

 Twentieth century advances in cancer research, op. cit., 299. 



®- Cancer in plants, Proc. 11th Internat. Cong, of Med., Section III, General 

 Pathology and Pathological Anatomy, reprint, 18. Citing Borrel's paper, Le cancer, 

 ler Cong. Int. Path, comparee 1(2): 640-641. 



