612 Third European Journey 



had many of the most distinguished biologists of Paris — Mangin, Mesnil, 

 Viala, Bloeringhem, Costantin, Guilliermond, Magrou, Foex, etc. They 

 hstened very intently and several took notes feverishly and when done I 

 received a good round of applause. Professor Mangin, director of the 

 garden, vv'ho introduced me in Professor MoUiard's absence, also closed 

 with some highly flattering remarks and asked to have the paper for Revue 

 generale des Sciences pures et applique es.''^ 



That evening, the first of two elaborate dinners given in Dr. 

 Smith's honor, took place at the home of Jean Magrou, sculptor 

 and brother of Dr. Magrou of the Pasteur Institute, with twelve 

 guests seated. The other, given at Dr. Calmette's home for 

 eighteen persons of great distinction in literary and scientific 

 circles of Paris, occurred two evenings later. Madame Mary 

 Duclaux and Dr. Pasteur Vallery-Radot were there, and among 

 the scientists were Mesnil, Besredka, Weinberg, Magrou, Bertrand, 

 Delezenne, Negre, and Calmette. 



While in Paris, Smith had many conferences with research men 

 about diseases of plants: pear blight; mosaic, white-spot, and 

 chancre of tobacco; crown gall; and others. At the Hotel Dieu, 

 the great hospital near Notre Dame, Professor Menetrier wel- 

 comed him and he became acquainted with Dr. C. Botelho, chief 

 of the cancer laboratory, and Dr. Hartmann, surgeon. To them 

 he showed his crown gall photographs, discussed whether cancer 

 is caused by a parasite and whether its spread in plant and animal 

 bodies is by apposition, and diagnostic methods by serum or 

 radium emanations. Dr. Hartmann was especially interested in 

 Smith's " photos showing results of chemical stimulation " in 

 crown gall.'*^ Dr. Menetrier showed Smith " a slide of stomach 

 carcinoma in a rat produced by injecting tar into the loin of the 

 rat at intervals (about 20 times) in course of a few months. After 

 six months he obtained a stomach carcinoma very definite with no 

 tar touching it. The tar is all on the outside of the stomach 

 muscles plainly to be seen. Contrary to statements made in the 

 first edition of his book Dr. Menetrier now says there is no growth 

 by apposition in cancer. He thinks there is no parasite in cancer. 

 Dr. Botelho, whose laboratory I next visited, believes there is a 

 parasite. He tells me," Smith wrote," 



■'^ Les maladies bacterriennes des plantes, 134-138, 193, Mar. 15, 1925. 

 "Journal, Jan. 24, 1925. 

 " Journal, Jan. 24, 1925. 



