Last Work. I-inai. Honors 6l3 



that someone has found that in tar cancer in mice all the tripanosomes 

 migrate to these sore spots. He says Dr. Mat^rou and the Surqeon with 

 whom he is working have discovered that tlie L;rowdi of crown^alls can be 

 prevented by exposing them to a certain kind of vibratory machine which 

 gives very long waves. He himself has dicovered a diagnostic method for 

 cancer. 



On January 31, Smitli went attain to Dr. Botelht^'s laboratory 

 and this time met Dr. K. Itchikawa who had spent a year and half 

 in Paris studying tar cancer at various laboratories including that 

 of Professor G. Roussy in the Ccole de Medicine. To Smith's 

 delight he found that Itchikawa planned to visit in May his 

 laboratory of pla-nt pathology. " He seemed pleased to meet me 

 and I certainly was to see him, because," wrote Smith, "^^ " he has 

 done splendid work on Tar Cancer. In Botelho's laboratory I read 

 his serum charts. He claims, with serum from cancer patients, to 

 obtain a definite diagnostic reaction," which he later demonstrated 

 for Smith. Dr. Smith took pages of notes on the diagnostic tests, 

 why some failed to give the reaction, the reagents used, and the 

 mixtures which gave the best results of various purposes, including 

 palliatives for hopeless cases abandoned by surgeons. Itchikawa 

 confided to Smith that, in tar cancers of rabbits, he had secured 

 confirmatory results of Botelho's method of diagnosing " invisible 

 cancers " and believed in it. He was told also that Dr. Hartmann 

 used the method in his surgical work.'" 



Dr. Weinberg of the Pasteur Institute invited Smith to see his 

 " many drawings and paintings showing result of the activities of 

 intestinal worms in various experimental animals. He [had] 

 proved that they can penetrate the musculars of the stomach and 

 intestine in some cases allowing bacteria to enter causing ulcers 

 and in one case a fibrous tumor." Since the w^ar, he had been 

 publishing and lecturing on anaerobic bacteria and gangrene.^" 



February 3 was also an important day since in the morning 

 Smith visited Dr. Magrou's tumor laboratory and the surgical 

 laboratories of the famous surgeon, Dr. Gosset, at the great 

 Salpetricre Hospital. His journal reads: 



Dr. Magrou showed me again the slide of Pelargonium tumor stained 



■'* Journal, Jan. 31, 1925. 



^' Some newer aspects of cancer research, op. cit., 595-596; Journal, Feb. 3, 4, 

 1925, Feb. 11, 1925. 



«" Journal, Feb. 2, 1925, Feb. 10, 1925. 



