Further RiisnARCHiis in Disi:asiis of Plants 559 



journey. They had attended several pleasant social affairs. At 

 Ann Arbor Dr. Smith sat several times for his portrait, an honor 

 arranged for by Dr. Harlcy Harris Bartlett, professor of botany 

 at the university and a close and good friend for many years. At 

 Cleveland they spent some time with Norman P. Buffett, brother 

 of Charlotte May Buffett Smith. From a research point of view 

 their Chicago stay had been " very profitable," and so immediately 

 Smith began to go forward with his studies. He first tried to 

 consult with Dr. George W. Crile of the famous Cleveland Clinic 

 at Euclid Avenue and 93rd Street. He was out of the city, so, 

 until his return, Smith spent his time consulting other doctors of 

 the Clinic and the Lakeside Hospital. On July 5 he had luncheon 

 with Dr. Crile who introduced him to more doctors and to Miss 

 Amy F. Rowland who was making some electrical conductivity 

 experiments with animal tissues in the laboratories. So interested 

 was Dr. Crile in Dr. Smith's work that he offered him "" all the 

 facilities of the laboratory " if Smith wished to make conductivity 

 tests on crown gall. Dr. and Mrs. Smith arrived in Washington 

 July 6, he highly elated and with a prepared insert on primary 

 liver tumors, and literature, for his paper on appositional growth 

 in crown gall tumors and in cancers.**" 



The following year, on March 8, he wrote to Dr. Bloodgood: 



I am in high feather this afternoon because I have discovered a paper 

 by Dr. H. T. Deelman of Amsterdam, in which he says that tar cancer 

 grows by apposition as well as invasively. His exact expression is that 

 there are two ways of growth, first, an invasive growth " aus sich heraus," 

 and second, a horizontal growth in all directions by cancerous conversion 

 of neighboring cells. What a pity I didn't know of this in time to make a 

 reference to it in my Journal of Cancer Research paper. He thinks Ribbert 

 and his followers are all wrong. He says that the neighboring cells of the 

 skin become first enlarged and then cancerous, just as I find in the crown 

 gall.^i 



In December 1922 Dr. and Mrs. Smith visited again in Ann 

 Arbor, and also this time at Lansing. To botanists and bacteri- 

 ologists, about sevent)'-five persons in the audience at Ann Arbor 

 and at least tsventy botanists at Lansing, he repeated his lecture 



" Appositional growth in crown-gall tumors and in cancers, Jour. Cancer Research 

 7: 1-105, 28 pis., 1922, Literature ref., pp. 47-49. 



'^ Smith told Bloodgood that Dr. Dceiman's paper was found in Klinische 

 Wochenschrift 1. Jahrg. Nr. 29, 15 July, 1922, pp. 1455-1457. 



