Last Work. Final Honors 621 



have great conhdcncc in tlicir results. Tliey think, just as I do, 

 tliat the cancer cells behave unlike normal cells, and contain 

 unlike substance." Smith's technical account of what he saw and 

 learned at Dr. Warburg's laboratory on March 1 1 tilled two pages 

 of closely written material in his journal. Furthermore, in two 

 addresses ""^ given after his arrival home, he was to describe this 

 work and estimate its value for the future. He knew he had met 

 a very able, great scientist. In 1931 Dr. Warburg would win the 

 Nobel prize in physiology and medicine for his discovery of the 

 character and mode of action of the respiratory ferment. Famous 

 today for his work on oxidation in the cell and the nature of the 

 flavine enzyme, he is known, too, for his discovery, with Dr. 

 Christian, of the secondary respiration ferment. Recently he has 

 been a visiting professor at the University of Illinois. There a 

 special laboratory was established for his work. 



From February 27 until March 2, every working day was given 

 by Smith to re-checking the research methods and results of Miss 

 Meyer, Dr. Auler, and Dr. Blumenthal. From March 2 through 

 March 4 Dr. and Mrs. Smith, accompanied by Dr. Blumenthal, 

 took a " pleasant and profitable " trip to Dresden. There the two 

 scientists went to the Siichsisches Serumwerk Aktiengesellschaft 

 where Smith met two high officials, Drs. Behlke and P. Galewsky, 

 and various assistants. He was shown their chemical laboratories 

 and work, and in the evening attended the Dresdener Medicinische 

 Gesellschaft meeting to hear a lantern slide illustrated lecture on 

 rat cancers due to PM given by Privat Docent Dr. Reichert of the 

 Serum Laboratory. After this event, Dr. Blumenthal entertained 

 eight guests, and the scientists were '" greatly interested " and 

 asked many questions of Dr. Smith about his crown gall work. By 

 this time he was much more convinced of the validity of the 

 Blumenthal PM malignancies. On February 27 practically every 

 doubt as to whether PM would produce tumors in plants had been 

 removed. But he had yet to be convinced that the rat-tumors were 

 really caused by PM. The possibility of " some unknown virus or 

 other irritation introduced along with PM and since propagated 

 by grafting " was still in his mind. " Once started," he said, 

 "' grafting to any number of generations is no evidence as to the 

 cause of a tumor." "' In a letter to Miss 'Hedges of his laboratory, 



"° Some newer aspects of cancer research, op. ci:., 596-597 ; Recent cancer research, 

 op. cit., 247, 255. 



^" Journal, Feb. 27, 1925. 



