632 Third European Journey 



most interesting and important research records. You may be 

 aware," he wrote, " that for forty years I have been preaching the 

 need of Comparative Pathology," and he requested that Smith 

 send him more of his reprints. German Sims Woodhead of the 

 pathological laboratory at Cambridge also had been interested in 

 Smith's work, especially his study of " Production of tumors in the 

 absence of parasites " (1920) . " You have taken up an interesting 

 subject," he wrote, " one that has very wide bearing." 



Dr. and Mrs. Smith arrived in London on the evening of March 

 31, and soon he visited the Middlesex Hospital cancer laboratories. 

 There he met several of the doctors, and with one. Dr. Helen 

 Chambers, a cancer research specialist, he discussed questions of 

 parasitism and immunity by x-ray, showed her his Blumenthal 

 rat-cancer slides, and she showed him " some of her rats inoculated 

 with Jensen's rat sarcoma." In sixty per cent of human breast 

 cancer cases, the parasite Demodex, he learned, was found asso- 

 ciated with the disease, and an appointment was arranged the next 

 day with " Surgeon Handley of breast cancer fame." Eight of 

 the doctors and surgeons saw his Blumenthal rat specimens. 

 Unable to locate Dr. Sambon at the Tropical School of Medicine, 

 he went on to officials and members of the famous staff of the 

 Imperial Cancer Research Fund. He wanted to find its director, 

 Dr. James Alexander Murray, but, he being out of the city. Smith 

 consulted with Dr. Findlay who showed him about the laboratories 

 and arranged an appointment with Dr. Murray for April 15. Dr. 

 Findlay gave him a copy of the Fund's 1923 report, and Smith 

 learned that he had " a note in The Lancet (April 4) reporting 

 three cases of skin cancer in mice from a single application of hot 

 tar (70°C)." Dr. Findlay then gave Dr. Smith some important 

 information: that " one of their research men (at a substation) has 

 found the virus of Rous's chicken sarcoma. This man's name 

 [was] Dr. Gye."^^^ 



Dr. Smith was not to meet Dr. Gye until after his conference 

 with Dr. Murray. Soon after their arrival in London, he and Mrs. 

 Smith had had dinner with Dr. and Mrs. Brierley, and on April 

 6 they went to Harpenden to enjoy two days at the Rothamsted 

 Experiment Station. At almost every point of their journey, they 

 had been entertained with teas and dinners, and this was no 



"^ Journal, Apr. 2, 3, 4, 1925. 



